Abstract: A powder storage and delivery system for a drug powder inhaler has a carrier disk with a blister shell sealed by a shear layer. A tab is adhered to the shear layer, underneath the blister shell. The carrier disk is placed into a dry powder inhaler. An actuator pushes against the tab, causing the shear layer to tear away, releasing the powder drug contents from the blister into the dry powder inhaler. A disk carrier has bursting blisters with a brittle blister shell sealed with a foil lid, and covered by a plate. An actuator moves against the plate, causing the plate to buckle and the blister shell to burst open, releasing powdered drug into the dry powder inhaler.

Abstract: A dry powder medicine inhaler has an impeller non-concentrically disposed in a mixing chamber. A motor spins the impeller at high speed. A plunger introduces a dose of powdered medicine into the chamber so that all powder particles are available for intermixing disaggregation and comminution. An aperture receives a first stream of air and passes it towards the mouthpiece for inhalation by the user. A wall has at least one aperture for diverting a portion of a main air stream into the aerosolizing chamber to mix with the particles to form a fine, low-density, low velocity, dry mist of powdered medicine for inhalation by the user.

Abstract: A dry powder medicine inhaler has an impeller non-concentrically disposed in a mixing chamber. A motor spins the impeller at high speed. A plunger introduces a dose of powdered medicine into the chamber so that all powder particles are available for intermixing disaggregation and comminution. An aperture receives a first stream of air and passes it towards the mouthpiece for inhalation by the user. A wall has at least one aperture for diverting a portion of a main air stream into the aerosolizing chamber to mix with the particles to form a fine, low-density, low velocity, dry mist of powdered medicine for inhalation by the user.

Abstract: Methods and compositions for the treatment of non-Ige-mediated inflammatory response or disease conditions are described.

Abstract: An apparatus for aerosolizing a dose of powdered medicine for inhalation, comprising in combination a solid core defining a diskshaped aerosolizing chamber, the chamber defined by spaced-apart, flat front and rear walls terminated by a circumferential wall, the core including a first end piece having formed therein a hollow mouth/nose piece at the front thereof, an impeller non-concentrically disposed in the chamber mounted on a shaft for high-speed powered rotation about a fixed axis, a plunger for instantaneously introducing a full dose of powdered medicine into the aerosolizing chamber so that all particles thereof are available for intermixing disaggregation and comminution, an aperture for receiving a first stream of air interior the core and passing it towards the mouthpiece for inhalation by the user, and, a wall having formed therein at least one aperture for diverting a portion of the first stream into a second stream of air for sweeping through the aerosolizing chamber to mix with the particles to f

Abstract: A portable hand-held spirometer capable of being accommodated in a pocket or handbag, comprising a chassis, an enclosed curved passageway in communication with the chassis including an inlet, for receiving the forced expiration of the user, and an outlet, through which the expiration may be exhausted, a vane pivotally mounted in the passageway, between the inlet and the outlet, for moving under the influence of the user's forced expiration from a first position closing off the passageway to a succession of other open positions forming an ever widening gap between the vane and part of the passageway as the vane moves therethrough, a bottom cover for incrementally measuring various positions of the vane, throughout its travel as a function of time, a device to convert the measurements to various diagnostic parameters applicable to the user's lung condition, and a device to report the values.