Abstract: Compounds, topical compositions and methods useful for preventing the penetration of toxic chemicals through the skin of a mammal are disclosed.The compounds of the invention provide an enhanced barrier for the skin of a mammal to further inhibit or decrease the passage of bioactive agents through the skin of a mammal either from the outside environment into the systems of said mammal or from the mammal into the outside environment.
Type:
Grant
Filed:
July 3, 1996
Date of Patent:
December 30, 1997
Assignee:
Durham Pharmaceuticals LLC
Inventors:
James V. Peck, Gevork Minaskanian, Mark C. Sleevi