Patents Assigned to Dynal Biotech ASA
  • Novel MHC molecule constructs, and methods of employing these constructs for diagnosis and therapy, and uses of MHC molecules
    Publication number: 20150329617
    Abstract: Novel compounds carrying ligands capable of ligating to counter receptors on relevant target cells are disclosed. The compounds possess a number of advantageous features, rendering them very suitable for a wide range of applications, including use as detection systems, detection of relevant target cells as well as in various methods. In particular, novel MHC molecule constructs comprising one or more MHC molecules are disclosed. The affinity and avidity of the MHC molecules of the constructs are surprisingly high. The possibility of presenting to the target cells a plurality of MHC molecules makes the MHC molecule constructs an extremely powerful tool e.g. in the field of diagnosis. The invention relates in general to the field of therapy, including therapeutic methods and therapeutic compositions. Also comprised by the present invention is the sample-mounted use of MHC molecules, MHC molecule multimers, and MHC molecule constructs.
    Type: Application
    Filed: March 13, 2002
    Publication date: November 19, 2015
    Applicants: DYNAL BIOTECH ASA, DAKO A/S
    Inventors: Lars Winther, Lars Oestergaard Petersen, Soeren Buus, Joergen Schoeller, Erik Ruud, Oeystein Aamellem
  • Process for the preparation of functionalised polymer particles
    Patent number: 7763689
    Abstract: A process for the preparation of amine-functionalized vinyl polymer particles which process comprises suspension polymerizing minostyrene together with at least one other vinylic monomer and optionally a crosslinking agent.
    Type: Grant
    Filed: August 21, 2007
    Date of Patent: July 27, 2010
    Assignee: Dynal Biotech ASA
    Inventors: Geir Fonnum, Ellen Weng, Elin Marie Aksnes, Rolf Nordal, Preben Cato Mørk, Svein Tøgersen, Julian Cockbain
  • Process
    Patent number: 7160707
    Abstract: A process for the preparation of coated polymer particles containing superparamagnetic crystals, said process comprising reacting porous, surface-functionalized, superparamagnetic crystal-containing polymer particles of diameter 0.5 to 1.8 ?m with at least one polyisocyanate and at least one diol or at least one epoxide.
    Type: Grant
    Filed: March 3, 2005
    Date of Patent: January 9, 2007
    Assignee: Dynal Biotech ASA
    Inventors: Geir Fonnum, Nini Kjus Hofsløkken, Elin Marie Aksnes, Lars Kilaas, Arvid Trygve Berge, Ruth Schmid, Jon Olav Bjorgum
  • Process
    Patent number: 6986913
    Abstract: A process for the preparation of coated polymer particles containing superparamagnetic crystals, said process comprising reacting porous, surface-functionalized, superparamagnetic crystal-containing polymer particles of diameter 0.5 to 1.8 ?m with at least one polyisocyanate and at least one diol or at least one epoxide.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: January 17, 2006
    Assignee: Dynal Biotech ASA
    Inventors: Geir Fonnum, Nini Kjus Hofsløkken, Elin Marie Aksnes, Lars Kilaas, Arvid Trygve Berge, Per Stenstad, Ruth Schmid, Jon Olav Bjorgum, Tom-Nils Nilsen
  • Process for the preparation of functionalized polymer particles
    Patent number: 6984702
    Abstract: A process for the preparation of amine-functionalized vinyl polymer particles which process comprises suspension polymerizing aminostyrene together with at least one other vinylic monomer and optionally a crosslinking agent.
    Type: Grant
    Filed: March 1, 2001
    Date of Patent: January 10, 2006
    Assignee: Dynal Biotech ASA
    Inventors: Geir Fonnum, Ellen Weng, Elin Marie Aksnes, Rolf Nordal, Preben Cato Mørk, Svein Tøgersen, Julian Cockbain
  • Particles
    Patent number: 6787233
    Abstract: The invention provides electroconductive particles comprising a styrene copolymer core and an external gold coating, characterised in that as said copolymer core is used a styrene copolymer comprising less than 50 wt. % styrene residues.
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: September 7, 2004
    Assignee: Dynal Biotech ASA
    Inventors: Astrid Evenrod Molteberg, Arvid Trygve Berge