Patents Assigned to Dynamis Therapeutics, Inc.
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Methods for maintaining or improving health, well-being and/or a physiological function in a subject
Patent number: 9555012Abstract: The invention relates to a method of treating or preventing a condition in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof. The invention further relates to a method of improving a physiological function in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof.Type: GrantFiled: August 8, 2013Date of Patent: January 31, 2017Assignee: Dynamis Therapeutics, Inc.Inventor: Annette Tobia -
Methods for maintaining or improving health, well-being and/or a physiological function in a subject
Patent number: 9446007Abstract: The invention relates to a method of treating or preventing a condition in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof. The invention further relates to a method of improving a physiological function in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof.Type: GrantFiled: March 30, 2015Date of Patent: September 20, 2016Assignees: Dynamis Therapeutics, Inc., Lankenau Institute for Medical ResearchInventors: Annette Tobia, Arturo Bravo Nuevo, Lisa Laury-Kleintop -
Methods for Maintaining or Improving Health, Well-Being and/or a Physiological Function in a Subject
Publication number: 20140045947Abstract: The invention relates to a method of treating or preventing a condition in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof. The invention further relates to a method of improving a physiological function in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof.Type: ApplicationFiled: August 8, 2013Publication date: February 13, 2014Applicant: Dynamis Therapeutics, Inc.Inventor: Annette Tobia -
Publication number: 20100310482Abstract: The invention relates to a method of removing 3-deoxyglucosone and other alpha-dicarbonyl sugars from skin. The invention further relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin. The invention also relates to methods of treating 3-deoxyglucosone and other alpha-dicarbonyl sugars associated diseases and disorders of skin.Type: ApplicationFiled: June 3, 2010Publication date: December 9, 2010Applicant: Dynamis Therapeutics, Inc.Inventors: Annette Tobia, Francis Kappler
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Publication number: 20100297046Abstract: The invention relates to compounds and methods for inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin, by way of fructosamine-3-kinase inhibition, thereby treating or prevention various diseases, disorders or conditions. Additionally, the invention relates to treatment of various diseases, disorders or conditions associated with or mediated by oxidative stress since 3DG induces ROS and AGEs, which are associated with the inflammatory response caused by oxidative stress.Type: ApplicationFiled: March 30, 2007Publication date: November 25, 2010Applicant: DYNAMIS THERAPEUTICS, INC.Inventors: Michael Schwartz, Francis Kappler, Bangying Su
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Patent number: 7749503Abstract: The invention relates to a method of removing 3-deoxyglucosone and other alpha-dicarbonyl sugars from skin. The invention further relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin. The invention also relates to methods of treating 3-deoxyglucosone and other alpha-dicarbonyl sugars associated diseases and disorders of skin.Type: GrantFiled: June 15, 2007Date of Patent: July 6, 2010Assignee: Dynamis Therapeutics, Inc.Inventors: Annette Tobia, Francis Kappler
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Patent number: 7671019Abstract: The invention relates to the discovery that 3-deoxyglucosone (3DG) and other alpha-dicarbonyl sugars associated diseases and disorders are present and produced in the skin. Further, the invention relates to the discovery that amadorase, an enzyme that mediates 3DG synthesis, is also present in the skin. Thus, the invention further relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin thereby treating or prevention various diseases, disorders or conditions. Additionally, the invention relates to treatment of various diseases, disorders or conditions associated with or mediated by oxidative stress since 3DG induces ROS and AGEs, which are associated with the inflammatory response caused by oxidative stress.Type: GrantFiled: October 15, 2004Date of Patent: March 2, 2010Assignee: Dynamis Therapeutics, Inc.Inventors: Annette Tobia, Francis Kappler
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Patent number: 7622117Abstract: The invention relates to a method of removing 3-deoxyglucosone and other alpha-dicarbonyl sugars from skin. The invention further relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin. The invention also relates to methods of treating 3-deoxyglucosone and other alpha-dicarbonyl sugars associated diseases and disorders of skin.Type: GrantFiled: July 18, 2002Date of Patent: November 24, 2009Assignee: Dynamis Therapeutics, Inc.Inventors: Annette Tobia, Francis Kappler
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Publication number: 20080292568Abstract: The invention relates to a method of removing 3-deoxyglucosone and other alpha-dicarbonyl sugars from skin. The invention further relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin. The invention also relates to methods of treating 3-deoxyglucosone and other alpha-dicarbonyl sugars associated diseases and disorders of skin.Type: ApplicationFiled: June 15, 2007Publication date: November 27, 2008Applicant: Dynamis Therapeutics, Inc.Inventors: Annette Tobia, Francis Kappler