Abstract: This document provides methods and materials for enhancing the storage capabilities of red blood cell preparations. For example, methods and materials for using CO2 to store red blood cells in a manner that (a) reduces the level of glucose or 2,3-DPG consumption of or reduces the level of 2,3-DPG production by a red blood cell preparation, (b) reduces the level of lactate formation by a red blood cell preparation, and/or (c) reduces the pH level of a red blood cell preparation are provided. Such methods and materials can result in prolonging the useful lifespan of the red blood cells of the red blood cell preparation. This document also provides methods and materials involved in prolonging useful storage of platelet preparations. For example, methods and materials for storing platelets in a manner that reduces platelet metabolism, that preserves platelet function, and/or that reduces the risk of bacterial contamination are provided.

Abstract: Systems and methods for lowering the core body temperature of subject are generally described. In certain embodiments, the core body temperature of a subject can be lowered by using a heat exchanger configured to cool an intubation gas that is transported to the subject via an intubation tube. The intubation tube used to deliver cooled intubation gas to the subject can include one or more features facilitating cooling of the subject. For example, in certain embodiments, the intubation tube may include multiple lumens. In some embodiments, one of the lumens can be used to deliver the relatively cool intubation gas and a second lumen can be used to transport relatively warm gas away from the patient's lungs. In certain embodiments, the system can be configured such that water (e.g., in the form of ice particles and/or liquid mist) can be delivered to the subject via the intubation tube, which can provide an enhanced cooling effect.

Abstract: Systems and methods for lowering the body temperature of a patient or inducing hypothermia are generally described. In certain embodiments, the core body temperature of a patient can be lowered by using a heat exchanger. In certain embodiments, the heat exchanger of configured to facilitate transfer of heat from an intubation gas to a cooling fluid prior to delivering the intubation gas to the patient (e.g., to the patient's lungs).

Abstract: Tissue patches and associated systems and methods are described. Certain embodiments are related to inventive systems and methods in which tissue patches can be made quickly and robustly without the use of complicated fabrication or sterilization equipment.

Abstract: Tissue patches and associated systems and methods are described. Certain embodiments are related to inventive systems and methods in which tissue patches can be made quickly and robustly without the use of complicated fabrication or sterilization equipment.

Abstract: Tissue patches and associated systems and methods are described. Certain embodiments are related to inventive systems and methods in which tissue patches can be made quickly and robustly without the use of complicated fabrication or sterilization equipment.

Abstract: This document provides methods and materials for enhancing the storage capabilities of red blood cell preparations. For example, methods and materials for using CO2 to store red blood cells in a manner that (a) reduces the level of glucose or 2,3-DPG consumption of or reduces the level of 2,3-DPG production by a red blood cell preparation, (b) reduces the level of lactate formation by a red blood cell preparation, and/or (c) reduces the pH level of a red blood cell preparation are provided. Such methods and materials can result in prolonging the useful lifespan of the red blood cells of the red blood cell preparation. This document also provides methods and materials involved in prolonging useful storage of platelet preparations. For example, methods and materials for storing platelets in a manner that reduces platelet metabolism, that preserves platelet function, and/or that reduces the risk of bacterial contamination are provided.