Patents Assigned to Dyncorp
  • Method for producing an adapted virus population from an African green monkey kidney cell line
    Patent number: 6117667
    Abstract: The invention described herein provides a method for selecting a novel African Green monkey kidney (AGMK) cell substrate, its cultivation and serial passage and its subsequent characterization. The invention provides a method for the use of the cell substrate in the isolation, growth and serial passage of a large number of viruses, particularly rotaviruses, enteroviruses, respiratory viruses and hepatitis A virus. The invention provides a method for the utilization of this AGMK cell substrate for the production of live and killed virus vaccines.
    Type: Grant
    Filed: June 21, 1999
    Date of Patent: September 12, 2000
    Assignees: Dyncorp, National Institutes of Health
    Inventors: Louis Potash, Robert M. Chanock, Robert H. Purcell, Albert Z. Kapikian
  • Method for producing a virus from an african green monkey kidney cell line
    Patent number: 6025182
    Abstract: A method for producing novel African Green Monkey Kidney (AGMK) cell lines is taught. These cell lines which are free of viable adventitious microbial agents are useful as substrates for viruses and for the preparation of viral vaccines.
    Type: Grant
    Filed: March 26, 1998
    Date of Patent: February 15, 2000
    Assignees: Dyncorp, National Institutes of Health
    Inventors: Louis Potash, Robert M. Chanock, Robert H. Purcell, Albert Z. Kapikian
  • Method of producing a virus vaccine from an African green monkey kidney cell line
    Patent number: 5911998
    Abstract: A method for producing novel African Green Monkey Kidney (AGMK) cell lines is taught. These cell lines which are free of viable adventitious microbial agents are useful as substrates for viruses and for the preparation of viral vaccines.
    Type: Grant
    Filed: January 29, 1997
    Date of Patent: June 15, 1999
    Assignees: Dyncorp, National Institutes of Health
    Inventors: Louis Potash, Robert M. Chanock, Robert H. Purcell, Albert Z. Kapikian
  • African green monkey kidney cell lines useful for maintaining viruses and for preparation of viral vaccines
    Patent number: 5646033
    Abstract: A novel African Green Monkey Kidney (AGMK) cell line is taught as well as a method for the preparation thereof. The cell line which is free of viable adventitious microbial agents is useful as a substrate for viruses and for the preparation of viral vaccines.
    Type: Grant
    Filed: November 30, 1994
    Date of Patent: July 8, 1997
    Assignees: Dyncorp, National Institutes of Health
    Inventors: Louis Potash, Robert M. Chanock, Robert H. Purcell, Albert Z. Kapikian