Patents Assigned to Dynport Vaccine Company LLC
  • Preparation of protective antigen
    Patent number: 8440427
    Abstract: A polynucleotide sequence is provided comprising a nucleic acid sequence encoding recombinant Protective Antigen (rPA). Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA.
    Type: Grant
    Filed: June 27, 2012
    Date of Patent: May 14, 2013
    Assignees: Health Protection Agency, Dynport Vaccine Company LLC
    Inventors: John Brehm, Ian McEntee, Philip Vincent, Nigel Allison, Rossalyn Brehm, George Jack, Michael Herbert, Barbara T. Solow, Juan Arroyo, Randall K. Lapcevich
  • Preparation of protective antigen
    Patent number: 8323927
    Abstract: A polynucleotide sequence is provided comprising a nucleic acid sequence encoding recombinant Protective Antigen (rPA). Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA.
    Type: Grant
    Filed: September 27, 2011
    Date of Patent: December 4, 2012
    Assignees: Health Protection Agency, Dynport Vaccine Company LLC
    Inventors: John Brehra, Ian McEntee, Philip Vincent, Nigel Allison, Rossalyn Brehm, George Jack, Michael Herbert, Barbara T. Solow, Juan Arroyo, Randall K. Lapcevich
  • Preparation of protective antigen
    Patent number: 8101735
    Abstract: A polynucleotide sequence is provided comprising a nucleic acid sequence encoding recombinant Protective Antigen (rPA). Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA.
    Type: Grant
    Filed: March 4, 2008
    Date of Patent: January 24, 2012
    Assignees: Health Protection Agency, Dynport Vaccine Company LLC
    Inventors: John Brehm, Ian McEntee, Philip Vincent, Nigel Allison, Rossalyn Brehm, George Jack, Michael Herbert, Barbara T. Solow, Juan Arroyo, Randall K. Lapcevich
  • protective antigen
    Patent number: 7355027
    Abstract: A polynucleotide sequence is provided, comprising: a nucleic acid sequence having at least 75% identity to SEQ ID NO: 1, wherein said nucleic acid sequence encodes recombinant Bacillus anthracis Protective Antigen (rPA); or a fragment of said nucleic acid sequence wherein said fragment encodes a fragment of recombinant Bacillus anthracis Protective Antigen (rPA). Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA or a fragment thereof. The invention further provides antigenic compositions and corresponding methods and uses for inducing an immune response.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: April 8, 2008
    Assignees: Dynport Vaccine Company LLC, Health Protection Agency
    Inventors: John Brehm, Ian McEntee, Philip Vincent, Nigel Allison, Rossalyn Brehm, George Jack, Michael Herbert, Barbara T. Solow, Juan Arroyo, Randall K. Lapcevich
  • PREPARATION OF PROTECTIVE ANTIGEN
    Publication number: 20080020001
    Abstract: A polynucleotide sequence is provided, comprising: a nucleic acid sequence having at least 75% identity to SEQ ID NO: 1, wherein said nucleic acid sequence encodes recombinant Bacillus anthracis Protective Antigen (rPA); or a fragment of said nucleic acid sequence wherein said fragment encodes a fragment of recombinant Bacillus anthracis Protective Antigen (rPA). Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA or a fragment thereof. The invention further provides antigenic compositions and corresponding methods and uses for inducing an immune response.
    Type: Application
    Filed: June 15, 2005
    Publication date: January 24, 2008
    Applicants: Health Protection Agency, Dynport Vaccine Company LLC
    Inventors: John Brehm, Ian McEntee, Philip Vincent, Nigel Allison, Rossalyn Brehm, George Jack, Michael Herbert, Barbara Solow, Juan Arroyo, Randall Lapcevich