Patents Assigned to E. I. du Pont de Nemours
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Publication number: 20190062382Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: October 1, 2018Publication date: February 28, 2019Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: JENNIFER BARRY, RYAN MICHAEL GERBER, LU LIU, AMY LUM, ERIC SCHEPERS, NASSER YALPANI, GENHAI ZHU
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Patent number: 10208298Abstract: A composition is disclosed that comprises at least one protein component of an RNA-guided endonuclease (RGEN) and at least one cell-penetrating peptide (CPP), wherein the RGEN protein component and CPP are covalently or non-covalently linked to each other in an RGEN protein-CPP complex. The RGEN protein-CPP complex can traverse (i) a cell membrane, or (ii) a cell wall and cell membrane, of a cell. The RGEN protein component of an RGEN protein-CPP complex in certain embodiments can be associated with a suitable RNA component to provide an RGEN capable of specific DNA targeting. Further disclosed are compositions comprising at least one protein component of a guide polynucleotide/Cas endonuclease complex and at least one CPP, as well as methods of delivering RGEN proteins into microbial cells, as well as methods of targeting DNA with RGENs.Type: GrantFiled: November 3, 2015Date of Patent: February 19, 2019Assignee: E.I. DU PONT DE NEMOURS AND COMPANYInventors: Ryan L. Frisch, Xiaochun Fan, Seung-Pyo Hong, Ethel Noland Jackson
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Patent number: 10202655Abstract: This invention relates to polynucleotide sequences encoding genes that can confer resistance to the plant pathogen Colletotrichum, which causes anthracnose stalk rot, leaf blight and top dieback in corn and other cereals. It further relates to plants and seeds of plants carrying chimeric genes comprising said polynucleotide sequences, which enhance or confer resistance to the plant pathogen Colletotrichum, and processes of making said plants and seeds. The invention further presents sequences that can be used as molecular markers that in turn can be used to identify the region of interest in corn lines resulting from new crosses and to quickly and efficiently introgress the genes from corn lines carrying said genes into other corn lines that do not carry said genes, in order to make them resistant to Colletotrichum and resistant to stalk rot.Type: GrantFiled: April 20, 2017Date of Patent: February 12, 2019Assignee: E. I. DU PONT DE NEMOURS AND COMPANYInventors: Karen E Broglie, Karlene H. Butler
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Patent number: 10202332Abstract: Disclosed are methods for preparing compounds of Formula 1 and 1A. The first method utilizes a benzyl carbamate amine protecting group and an intermediate of Formula 4. The second method utilizes a tert-butyl carbamate amine protecting group and an intermediate of Formula 7. The third method utilizes a dibenzyl amine protecting group. Also disclosed is a compound, phenylmethyl N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]carbamate (a compound of Formula 4). Further disclosed is a method for preparing a compound of Formula 14 from a compound of Formula 15 and a compound of Formula 1 or 1A.Type: GrantFiled: September 23, 2011Date of Patent: February 12, 2019Assignee: E. I. du Pont de Nemours and CompanyInventor: Joerg Bruening
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Publication number: 20190040432Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.Type: ApplicationFiled: October 18, 2018Publication date: February 7, 2019Applicant: E I DU PONT DE NEMOURS AND COMPANYInventors: MARK S. PAYNE, YEFIM BRUN, HONGXIAN HE, THOMAS SCHOLZ
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Publication number: 20190040413Abstract: The disclosure provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-032218-9 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.Type: ApplicationFiled: October 23, 2018Publication date: February 7, 2019Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: MARY BEATTY, KENT BRINK, VIRGINIA CRANE, SCOTT DIEHN, ALBERT LU, GREGORY J. YOUNG
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Publication number: 20190040405Abstract: Compositions and methods are provided for genome modification of a target sequence in the genome of a plant or plant cell. The methods and compositions employ a guide RNA/Cas endonuclease system to provide an effective system for modifying or altering target sites within the genome of a plant, plant cell or seed. Also provided are compositions and methods employing a guide polynucleotide/Cas endonuclease system for genome modification of a nucleotide sequence in the genome of a cell or organism, for gene editing, and/or for inserting or deleting a polynucleotide of interest into or from the genome of a cell or organism. Once a genomic target site is identified, a variety of methods can be employed to further modify the target sites such that they contain a variety of polynucleotides of interest. Breeding methods and methods for selecting plants utilizing a two component RNA guide and Cas endonuclease system are also disclosed.Type: ApplicationFiled: September 13, 2018Publication date: February 7, 2019Applicants: E. I. DU PONT DE NEMOURS AND COMPANY, PIONEER HI-BRED INTERNATIONAL, INC.Inventors: ANDREW MARK CIGAN, SAVERIO CARL FALCO, HUIRONG GAO, ZHONGSEN LI, ZHAN-BIN LIU, LESZEK ALEKSANDER LYZNIK, JINRUI SHI, SERGEI SVITASHEV, JOSHUA K. YOUNG
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Patent number: 10196531Abstract: The present disclosure provides an ink for inkjet printing. The ink contains an aqueous vehicle, a dispersed pigment colorant, a dispersed polyurethane polymer, and a dispersed olefin ionic copolymer. The ink exhibits improved short-term durability.Type: GrantFiled: December 15, 2014Date of Patent: February 5, 2019Assignee: E I DU PONT DE NEMOURS AND COMPANYInventors: Christian Jackson, C. Chad Roberts
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Patent number: 10199577Abstract: There is disclosed a compound having Formula I or Formula I?: In Formula I and Formula I?: Ar1 and Ar2 are the same or different and are aryl groups; R1 through R5 are independently the same or different at each occurrence and are D, F, alkyl groups, aryl groups, alkoxy groups, silyl groups, or crosslinkable groups; R6 is H, D, or halogen; a through e are independently an integer from 0 to 4; f is 1 or 2; g is 0, 1 or 2; h is 1 or 2; and n is an integer greater than 0.Type: GrantFiled: October 25, 2016Date of Patent: February 5, 2019Assignee: E I DU PONT DE NEMOURS AND COMPANYInventors: Kyung-Ho Park, Nora Sabina Radu, Gary A Johansson, Adam Fennimore, William J Delaney, Daniel David LeCloux
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Patent number: 10189950Abstract: This invention is directed to polyimide-based polymer thick film compositions and particularly non-fluorinated polyimide-based polymer thick film compositions. These compositions are comprised of certain polyimide polymers and certain solvents. In some embodiments various functional components are added to the composition to provide compositions that can be used to form various elements of an electrical circuit.Type: GrantFiled: December 12, 2016Date of Patent: January 29, 2019Assignee: E I DU PONT DE NEMOURS AND COMPANYInventors: Seigi Suh, Haixin Yang
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Patent number: 10190079Abstract: Compositions comprising cellulase and at least one poly alpha-1,3-glucan ether compound having a degree of substitution with a positively charged organic group of about 0.05-3.0 are disclosed. Such compositions can be dry or aqueous, the latter of which can have a viscosity of at least about 10 cPs. The disclosed composition can be in the form of a personal care product, household product, or industrial product, for example. Also disclosed are a method for preparing an aqueous composition comprising cellulase and a poly alpha-1,3-glucan ether compound, and a method of treating a material such as fabric by contacting it with this aqueous composition.Type: GrantFiled: June 30, 2017Date of Patent: January 29, 2019Assignee: E I DU PONT DE NEMOURS AND COMPANYInventors: Kevin D. Nagy, Ayrookaran J. Poulose, T. Joseph Dennes, Perry G. Caimi, Jayme L. Paullin, Susan Marie Hennessey
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Patent number: 10193070Abstract: There is disclosed a compound having Formula I, Formula II, Formula III, Formula VIII, Formula IX, or Formula X The variables are described in detail in the application.Type: GrantFiled: October 20, 2015Date of Patent: January 29, 2019Assignee: E I DU PONT DE NEMOURS AND COMPANYInventors: Weiying Gao, Michael Henry Howard, Jr., Viacheslav V. Diev, Weishi Wu, Hong Meng
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Patent number: 10190198Abstract: A thick film paste comprising at least one particulate platinum (alloy), at least one metal compound, and an organic vehicle, wherein the at least one metal compound is selected from the group consisting of in each case particulate NiO, SiO2, RuO2, Rh2O3, IrO2, Cu2O, CuO, TiO2, ZrO2, PbO, SnO2, CeO2, Al2O3, MgO, MnO2 and MoO2, and metal compounds capable of forming a metal oxide on firing, the metal oxide being selected from the group consisting of NiO, SiO2, RuO2, Rh2O3, IrO2, Cu2O, CuO, TiO2, ZrO2, PbO, SnO2, CeO2, Al2O3, MgO, MnO2 and MoO2.Type: GrantFiled: August 17, 2017Date of Patent: January 29, 2019Assignee: E I DU PONT DE NEMOURS AND COMPANYInventors: Howard David Glicksman, Adele Amelia Pliscott
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Patent number: 10190134Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Pentatomidae plant pest, decrease the expression of a target sequence in the pest. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: 6-12, 18-40 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.Type: GrantFiled: March 13, 2014Date of Patent: January 29, 2019Assignee: E I DU PONT DE NEMOURS AND COMPANYInventors: Brian McGonigle, James Kevin Presnail, Navdeep Singh Mutti
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Patent number: 10190179Abstract: The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-004114-3 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.Type: GrantFiled: September 15, 2017Date of Patent: January 29, 2019Assignees: PIONEER HI-BRED INTERNATIONAL, INC., E I DU PONT DE NEMOURS AND COMPANYInventors: Scott Diehn, Albert L. Lu, Timothy M. Nowatzki, Douglas S. Nubel, M. Alejandra Pascual, James C. Register, III, Christopher J. Scelonge, Joshua K. Young, Cathy Xiaoyan Zhong, Erin L. Crowgey
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Patent number: 10186353Abstract: Laminate structure suitable for use as electrical insulation comprising: a) a corona-resistant layer comprising 90 to 99 weight percent uniformly distributed calcined mica and 1 to 10 weight percent aramid material, the aramid material being in the form of floc, fibrid, or mixtures thereof; b) a support layer comprising unidirectional or woven filament yarns, the support layer having a first and second face; and c) a resin-compatible layer comprising 60 to 80 weight percent uniformly distributed uncalcined mica and 20 to 40 weight percent aramid material, the aramid material being in the form of floc, fibrid, or mixtures thereof; wherein the first face of the support layer is directly bound to the corona-resistant layer and the second face of the support layer is directly bound to the resin-compatible layer; the laminate structure having a total mica content of 60 weight percent or greater.Type: GrantFiled: June 21, 2016Date of Patent: January 22, 2019Assignee: E I DU PONT DE NEMOURS AND COMPANYInventors: Byoung Sam Kang, Sang Woo Lee
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Patent number: 10186494Abstract: An electric component comprising a terminal electrode and a hot-melt polymer layer formed on the terminal electrode, wherein the hot-melt polymer layer comprises (i) 100 parts by weight of a metal powder and (ii) 1 to 30 parts by weight of a polymer, wherein melt mass-flow rate (MFR) of the polymer is 0.5 to 20 g/10 min. at 120 to 200° C. and 0.3 to 8 kgf.Type: GrantFiled: July 12, 2017Date of Patent: January 22, 2019Assignee: E I DU PONT DE NEMOURS AND COMPANYInventor: Akira Inaba
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Publication number: 20190014779Abstract: Disclosed are compounds of Formulae 1, 1a, 1b and 2, wherein R1, R1a, R1b, R2, R3 and R4 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formulae 1, 1a and 1b, and methods for controlling a parasitic nematode comprising contacting the parasitic nematode or its environment with a biologically effective amount of a compound or composition of Formulae 1, 1a, 1b and 2.Type: ApplicationFiled: December 8, 2016Publication date: January 17, 2019Applicant: E. I. Du Pont De Nemours and CompanyInventors: George Philip LAHM, Andrew Jon DEANGELIS, Matthew James CAMPBELL
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Patent number: 10166754Abstract: The invention pertains to a printing form and a process for preparing a polymeric printing form from a curable composition that includes a multifunctional urethane in a specified reactive group equivalent weight range, and an initiator. The process includes coating the curable composition onto a supporting substrate, such as a print cylinder, to form a layer, curing the layer with heat or by exposure to actinic radiation, and engraving the resulting cured layer to form at least one printing cell in the cured layer. The process prepares novel polymeric printing forms, particularly novel polymeric gravure printing forms, having a cured polymer-based composition layer that is engravable, resistant to solvent inks, and capable of printing gravure-quality images. The present invention shortens the time to prepare gravure printing cylinders and removes the need for and disposal of toxic heavy metals such as copper and chrome associated with conventional gravure print cylinder preparation.Type: GrantFiled: February 20, 2018Date of Patent: January 1, 2019Assignee: E I DU PONT DE NEMOURS AND COMPANYInventors: Steven W Shuey, Adrian Lungu, Mukesh C Shah, Garret D Figuly
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Publication number: 20180371479Abstract: Compositions and methods are provided for genome modification of a target sequence in the genome of a plant or plant cell. The methods and compositions employ a guide RNA/Cas endonuclease system to provide an effective system for modifying or altering target sites within the genome of a plant, plant cell or seed. Also provided are compositions and methods employing a guide polynucleotide/Cas endonuclease system for genome modification of a nucleotide sequence in the genome of a cell or organism, for gene editing, and/or for inserting or deleting a polynucleotide of interest into or from the genome of a cell or organism. Once a genomic target site is identified, a variety of methods can be employed to further modify the target sites such that they contain a variety of polynucleotides of interest. Breeding methods and methods for selecting plants utilizing a two component RNA guide and Cas endonuclease system are also disclosed.Type: ApplicationFiled: August 3, 2018Publication date: December 27, 2018Applicants: E. I. DU PONT DE NEMOURS AND COMPANY, PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Andrew Mark Cigan, Saverio Carl Falco, Huirong Gao, Zhongsen Li, Zhan-Bin Liu, L. Aleksander Lyznik, Jinrui Shi, Sergei Svitashev, Joshua K. Young