Abstract: A plastic annular disk has a convex exterior surface upon which is situated an adhesive wafer. A removable protective shield is formed to have a substantially wrinkle-free surface with a contour identical to that of the convex surface. The disk and wafer are placed in a vacuum chamber, below a planar plastic sheet. The top of the chamber is heated. The space above the sheet is evacuated to draw the sheet against the heated surface. The remaining portion of the chamber is then evacuated to eliminate air between the wafer and disk. Lastly, the top of the chamber is vented such that the heated sheet is pressed over the wafer and disk.

Abstract: In the first embodiment, the faceplate coupling ring is of conventional design and includes an axially extending rib with a radially outwardly extending rim and a radially inwardly extending deflectable sealing strip. The pouch coupling ring includes inner and outer spaced walls, forming a channel for receiving the rib. First and second protrusions extend inwardly from points on the interior surface of the walls proximate the ends thereof. The first protrusion cooperates with the rim and the second protrusion cooperates with the tip of the sealing strip, to securely retain the rib within the channel. The walls of the channel have reduced thickness and are easily deflectable as the rib is inserted into the channel, such that coupling of the rings is facilitated but decoupling requires the conventional amount of force due to the second protrusion.

Abstract: An annular mounting member is bonded to the pouch wall to define a vent opening. The mounting member is made of material which is compatable with the pouch film and has a smooth exterior surface adapted to facilitate removable mounting of an adhesive coated element in alignment with the opening. The element may be a deodorizing filter assembly including a filter disk surrounded by an annular border member coated with pressure sensitive adhesive or a gas impermeable cover member designed to close the vent.

Abstract: To minimize trauma after surgery, a clamp is employed to sealingly engage specially configured coupling rings mounted on the adhesive faceplate and the collection pouch, respectively. Each of the coupling rings includes a radially extending annular projection. The circular clamp is designed to surround the coupling rings and receive the projections within an annular recess. The projections and recess have oppositely oriented camming surfaces which cooperates to draw the coupling rings toward each other as the clamp is tightened. The clamp is locked by a toggle clasp connected by a living hinge, a pin and socket arrangement, a serrated clasp or a change purse type clasp. An adaptor can be employed so that the clamp can be used with a pouch with a conventionally configured coupling ring.

Abstract: First and second annular interengaging parts releasably connect the pouch and adhesive-backed label. A member is provided for mounting one of the parts to the label, at a normal position proximate the surface of the label. The member includes a ring-shaped section, spaced from the part, which is adapted to be affixed to the surface of the label, and an expandable section, preferably including one or more accordion-like folds, interposed between the ring-shaped section and the part, to permit the part to be displaced relative to its normal position. The member will return to its normal position unless a detachable element is inserted beneath the member to retain the part in the displaced position. The other interengaging part may be provided with a flange-like portion situated to cover the expandable section, when the parts interengage, to protect the expandable section from waste material. Auxiliary interengaging parts may be provided to prevent accidental detachment and aid in supporting the pouch.

Abstract: The container has an elongated port section formed of a flexible cylindrical wall. A first tube member is lodged within the wall at a location spaced from the end thereof. A second tube member is forceably inserted within the first tube member, engaging a section of the wall therebetween. The engaged wall section may include a double wall thickness. One of the tube members is composed of substantially non-elastic material and the other is composed of relatively elastic material. The elastic member will deform so as to tightly seal the wall section. A detent may be present on one of the tube members to cooperate with a detent receiving recess on the other to enhance the strength of the seal. Any conventional drain valve or tubing can be connected to the protruding end of the second tube member.

Abstract: Adhesive pouch connecting rings with radially extending gripping portions are formed and stacked in angularly offset relation on a plurality of ostomy faceplates in a highly automated fashion. Sets of rings are die cut from a continuous adhesive coated sheet. Each set includes a plurality of spaced, identically oriented rings, in an arcuate pattern across the sheet. The sheet is intermittently advanced to bring the sets, one at a time, into alignment with faceplates located on a round platform. The platform is indexed to move the faceplates stepwise through a path coincident with the pattern of the ring sets. Each time the platform is indexed, a set of rings is removed from the sheet and the rings are placed on the respective faceplates, each in proper angular relation with the previous rings. Faceplates with a full complement of rings are removed from the platform.

Abstract: 7-Oxabicyclo(2.2.1)heptane hydroxamic acid derivatives are disclosed having the general formula ##STR1## wherein R.sub.1 is hydrogen, lower alkyl, aryl, aralkyl or alkenyl; R.sub.2 is hydrogen, lower alkyl, alkanoyl or aroyl; R.sub.3 is lower alkyl, alkenyl or alkynyl; A is --CH.sub.2 --CH.dbd.CH-- or a single bond; and n is an integer from 0 to 9, with the proviso that when A is a single bond, n is an integer from 1 to 9; and including all stereoisomers and pharmaceutically acceptable salts thereof.These new compounds have been found to simultaneously inhibit the arachidonic acid enzymes cyclooxygenase and 5-lipoxygenase and are therefore useful as antiinflammatory, antiasthma and antipsoriatic agents.

Abstract: An insert, having a non-heat sealable surface, is affixed to a first thin film wall. The first wall is aligned with a second thin film wall, with the non-heat sealable surface of the insert facing the interior surface of the second wall. The walls are welded along their periphery to form the contour of the pouch. An adhesive-backed label is then welded to the exterior of the second wall. The insert prevents the interior surfaces of the walls from being sealed together as the adhesive-backed label is welded, simplifying the manufacturing process. The non-heat sealable surface of the insert may be composed of a low friction material to facilitate movement of solid waste within the pouch.