Patents Assigned to Easel Biotechnologies, LLC
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Patent number: 10676762Abstract: Methods and systems for the production of alcohols are described. A two stage process is utilized, where fermentation in a first stage produces an intermediate product, such as an amino acid or organic acid, from a carbon containing feedstock. A second stage produces alcohol by fermentation of this intermediate product.Type: GrantFiled: January 31, 2019Date of Patent: June 9, 2020Assignee: EASEL BIOTECHNOLOGIES LLCInventors: Yi-Xin Huo, Kwang Myung Cho
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Patent number: 10450589Abstract: An improved process for alcohol production includes microbial fermentation using a genetically modified microorganism to produce substantial quantities of aldehydes that are stripped from the fermentation medium and condensed. So produced aldehydes are converted in an ex vivo process to corresponding alcohols.Type: GrantFiled: June 11, 2017Date of Patent: October 22, 2019Assignee: Easel Biotechnologies, LLCInventors: Wendy M. Higashide, Kwang Myung Cho, Shahrooz Rabizadeh
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Patent number: 10385366Abstract: Systems, methods, and metabolically engineered microorganisms are contemplated in which low molecular weight gases, and especially methane and syngas are used as a carbon source, and in which CO2 or formaldehyde and reduction equivalents are generated for use in in vivo production of the value products.Type: GrantFiled: October 11, 2018Date of Patent: August 20, 2019Assignee: Easel Biotechnologies, LLCInventors: Yi-Xin Huo, Lars Erik Ulf Rohlin, Shahrooz Rabizadeh
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Patent number: 10385328Abstract: Genetically engineered cells and methods are presented that allow for the production of various value products from CO2. Contemplated cells have a CBB cycle that is genetically modified such that two molecules of CO2 fixed in the CBB cycle can be withdrawn from the modified CBB cycle as a single C2 compound. In contemplated aspects a CBB cycle includes an enzymatic activity that generates the single C2 compound from a compound of the CBB cycle, while further modifications to the CBB cycle will not introduce additional recombinant enzymatic activity/activities outside the already existing catalytic activities in the CBB cycle.Type: GrantFiled: March 28, 2018Date of Patent: August 20, 2019Assignee: Easel Biotechnologies, LLCInventors: Yi-Xin Huo, Benjamin Schilling, Shahrooz Rabizadeh
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Publication number: 20190161775Abstract: Methods and systems for the production of alcohols are described. A two stage process is utilized, where fermentation in a first stage produces an intermediate product, such as an amino acid or organic acid, from a carbon containing feedstock. A second stage produces alcohol by fermentation of this intermediate product.Type: ApplicationFiled: January 31, 2019Publication date: May 30, 2019Applicant: Easel Biotechnologies, LLCInventors: Yi-Xin HUO, Kwang Myung CHO
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Patent number: 10233467Abstract: Methods and systems for the production of alcohols are described. A two stage process is utilized, where fermentation in a first stage produces an intermediate product, such as an amino acid or organic acid, from a carbon containing feedstock. A second stage produces alcohol by fermentation of this intermediate product.Type: GrantFiled: August 14, 2013Date of Patent: March 19, 2019Assignee: Easel Biotechnologies, LLCInventors: Yi-Xin Huo, Kwang Myung Cho
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Patent number: 10113160Abstract: Genetically engineered cells and methods are presented that allow for the production of various value products from CO2. Contemplated cells have a CBB cycle that is genetically modified such that two molecules of CO2 fixed in the CBB cycle can be withdrawn from the modified CBB cycle as a single C2 compound. In contemplated aspects a CBB cycle includes an enzymatic activity that generates the single C2 compound from a compound of the CBB cycle, while further modifications to the CBB cycle will not introduce additional recombinant enzymatic activity/activities outside the already existing catalytic activities in the CBB cycle.Type: GrantFiled: January 30, 2015Date of Patent: October 30, 2018Assignee: Easel Biotechnologies, LLCInventors: Yi-Xin Huo, Benjamin Schilling, Shahrooz Rabizadeh
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Patent number: 10106825Abstract: Systems, methods, and metabolically engineered microorganisms are contemplated in which low molecular weight gases, and especially methane and syngas are used as a carbon source, and in which CO2 or formaldehyde and reduction equivalents are generated for use in in vivo production of the value products.Type: GrantFiled: October 27, 2016Date of Patent: October 23, 2018Assignee: Easel Biotechnologies, LLCInventors: Yi-Xin Huo, Lars Erik Ulf Rohlin, Shahrooz Rabizadeh
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Publication number: 20180010155Abstract: Microorganisms and methods of producing n-butyraldehyde with enhanced yields are presented in which a microorganism is engineered to enhance the conversion of a carbon source into n-butyraldehyde. The n-butyraldehyde is recovered by way of a gas stripping process that occurs during the conversion process, providing significantly greater product yield than post-fermentation recovery of n-butyraldehyde alone.Type: ApplicationFiled: September 7, 2017Publication date: January 11, 2018Applicant: Easel Biotechnologies, LLCInventors: Kwang Myung Cho, Wendy Higashide, Chrissie Lee, Shahrooz Rabizadeh
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Patent number: 9777297Abstract: Microorganisms and methods of producing n-butyraldehyde with enhanced yields are presented in which a microorganism is engineered to enhance the conversion of a carbon source into n-butyraldehyde. The n-butyraldehyde is recovered by way of a gas stripping process that occurs during the conversion process, providing significantly greater product yield than post-fermentation recovery of n-butyraldehyde alone.Type: GrantFiled: November 2, 2012Date of Patent: October 3, 2017Assignee: EASEL BIOTECHNOLOGIES, LLCInventors: Kwang Myung Cho, Wendy Higashide, Chrissie Lee, Shahrooz Rabizadeh
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Patent number: 9708631Abstract: An improved process for alcohol production includes microbial fermentation using a genetically modified microorganism to produce substantial quantities of aldehydes that are stripped from the fermentation medium and condensed. So produced aldehydes are converted in an ex vivo process to corresponding alcohols.Type: GrantFiled: September 17, 2015Date of Patent: July 18, 2017Assignee: Easel Biotechnologies, LLCInventors: Wendy M. Higashide, Kwang Myung Cho, Shahrooz Rabizadeh
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Patent number: 9512450Abstract: Systems, methods, and metabolically engineered microorganisms are contemplated in which low molecular weight gases, and especially methane and syngas are used as a carbon source, and in which CO2 or formaldehyde and reduction equivalents are generated for use in in vivo production of the value products.Type: GrantFiled: February 24, 2014Date of Patent: December 6, 2016Assignee: Easel Biotechnologies, LLCInventors: Yi-Xin Huo, Lars Erik Ulf Rohlin, Shahrooz Rabizadeh
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Publication number: 20160348086Abstract: Genetically engineered cells and methods are presented that allow for the production of various value products from CO2. Contemplated cells have a CBB cycle that is genetically modified such that two molecules of CO2 fixed in the CBB cycle can be withdrawn from the modified CBB cycle as a single C2 compound. In contemplated aspects a CBB cycle includes an enzymatic activity that generates the single C2 compound from a compound of the CBB cycle, while further modifications to the CBB cycle will not introduce additional recombinant enzymatic activity/activities outside the already existing catalytic activities in the CBB cycle.Type: ApplicationFiled: January 30, 2015Publication date: December 1, 2016Applicant: Easel Biotechnologies, LLCInventors: Yi-Xin Huo, Benjamin Schilling, Shahrooz Rabizadeh
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Patent number: 9206443Abstract: An improved process for alcohol production includes microbial fermentation using a genetically modified microorganism to produce substantial quantities of aldehydes that are stripped from the fermentation medium and condensed. So produced aldehydes are converted in an ex vivo process to corresponding alcohols.Type: GrantFiled: March 14, 2012Date of Patent: December 8, 2015Assignee: Easel Biotechnologies, LLCInventors: Wendy M. Higashide, Kwang Myung Cho, Shahrooz Rabizadeh
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Publication number: 20140011231Abstract: An improved process for alcohol production includes microbial fermentation using a genetically modified microorganism to produce substantial quantities of aldehydes that are stripped from the fermentation medium and condensed. So produced aldehydes are converted in an ex vivo process to corresponding alcohols.Type: ApplicationFiled: March 14, 2012Publication date: January 9, 2014Applicant: Easel Biotechnologies, LLCInventors: Wendy M. Higashide, Kwang Myung Cho, Shahrooz Rabizadeh