Patents Assigned to Easel Biotechnologies, LLC
  • Patent number: 10676762
    Abstract: Methods and systems for the production of alcohols are described. A two stage process is utilized, where fermentation in a first stage produces an intermediate product, such as an amino acid or organic acid, from a carbon containing feedstock. A second stage produces alcohol by fermentation of this intermediate product.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: June 9, 2020
    Assignee: EASEL BIOTECHNOLOGIES LLC
    Inventors: Yi-Xin Huo, Kwang Myung Cho
  • Patent number: 10450589
    Abstract: An improved process for alcohol production includes microbial fermentation using a genetically modified microorganism to produce substantial quantities of aldehydes that are stripped from the fermentation medium and condensed. So produced aldehydes are converted in an ex vivo process to corresponding alcohols.
    Type: Grant
    Filed: June 11, 2017
    Date of Patent: October 22, 2019
    Assignee: Easel Biotechnologies, LLC
    Inventors: Wendy M. Higashide, Kwang Myung Cho, Shahrooz Rabizadeh
  • Patent number: 10385366
    Abstract: Systems, methods, and metabolically engineered microorganisms are contemplated in which low molecular weight gases, and especially methane and syngas are used as a carbon source, and in which CO2 or formaldehyde and reduction equivalents are generated for use in in vivo production of the value products.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: August 20, 2019
    Assignee: Easel Biotechnologies, LLC
    Inventors: Yi-Xin Huo, Lars Erik Ulf Rohlin, Shahrooz Rabizadeh
  • Patent number: 10385328
    Abstract: Genetically engineered cells and methods are presented that allow for the production of various value products from CO2. Contemplated cells have a CBB cycle that is genetically modified such that two molecules of CO2 fixed in the CBB cycle can be withdrawn from the modified CBB cycle as a single C2 compound. In contemplated aspects a CBB cycle includes an enzymatic activity that generates the single C2 compound from a compound of the CBB cycle, while further modifications to the CBB cycle will not introduce additional recombinant enzymatic activity/activities outside the already existing catalytic activities in the CBB cycle.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: August 20, 2019
    Assignee: Easel Biotechnologies, LLC
    Inventors: Yi-Xin Huo, Benjamin Schilling, Shahrooz Rabizadeh
  • Publication number: 20190161775
    Abstract: Methods and systems for the production of alcohols are described. A two stage process is utilized, where fermentation in a first stage produces an intermediate product, such as an amino acid or organic acid, from a carbon containing feedstock. A second stage produces alcohol by fermentation of this intermediate product.
    Type: Application
    Filed: January 31, 2019
    Publication date: May 30, 2019
    Applicant: Easel Biotechnologies, LLC
    Inventors: Yi-Xin HUO, Kwang Myung CHO
  • Patent number: 10233467
    Abstract: Methods and systems for the production of alcohols are described. A two stage process is utilized, where fermentation in a first stage produces an intermediate product, such as an amino acid or organic acid, from a carbon containing feedstock. A second stage produces alcohol by fermentation of this intermediate product.
    Type: Grant
    Filed: August 14, 2013
    Date of Patent: March 19, 2019
    Assignee: Easel Biotechnologies, LLC
    Inventors: Yi-Xin Huo, Kwang Myung Cho
  • Patent number: 10113160
    Abstract: Genetically engineered cells and methods are presented that allow for the production of various value products from CO2. Contemplated cells have a CBB cycle that is genetically modified such that two molecules of CO2 fixed in the CBB cycle can be withdrawn from the modified CBB cycle as a single C2 compound. In contemplated aspects a CBB cycle includes an enzymatic activity that generates the single C2 compound from a compound of the CBB cycle, while further modifications to the CBB cycle will not introduce additional recombinant enzymatic activity/activities outside the already existing catalytic activities in the CBB cycle.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: October 30, 2018
    Assignee: Easel Biotechnologies, LLC
    Inventors: Yi-Xin Huo, Benjamin Schilling, Shahrooz Rabizadeh
  • Patent number: 10106825
    Abstract: Systems, methods, and metabolically engineered microorganisms are contemplated in which low molecular weight gases, and especially methane and syngas are used as a carbon source, and in which CO2 or formaldehyde and reduction equivalents are generated for use in in vivo production of the value products.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: October 23, 2018
    Assignee: Easel Biotechnologies, LLC
    Inventors: Yi-Xin Huo, Lars Erik Ulf Rohlin, Shahrooz Rabizadeh
  • Publication number: 20180010155
    Abstract: Microorganisms and methods of producing n-butyraldehyde with enhanced yields are presented in which a microorganism is engineered to enhance the conversion of a carbon source into n-butyraldehyde. The n-butyraldehyde is recovered by way of a gas stripping process that occurs during the conversion process, providing significantly greater product yield than post-fermentation recovery of n-butyraldehyde alone.
    Type: Application
    Filed: September 7, 2017
    Publication date: January 11, 2018
    Applicant: Easel Biotechnologies, LLC
    Inventors: Kwang Myung Cho, Wendy Higashide, Chrissie Lee, Shahrooz Rabizadeh
  • Patent number: 9777297
    Abstract: Microorganisms and methods of producing n-butyraldehyde with enhanced yields are presented in which a microorganism is engineered to enhance the conversion of a carbon source into n-butyraldehyde. The n-butyraldehyde is recovered by way of a gas stripping process that occurs during the conversion process, providing significantly greater product yield than post-fermentation recovery of n-butyraldehyde alone.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: October 3, 2017
    Assignee: EASEL BIOTECHNOLOGIES, LLC
    Inventors: Kwang Myung Cho, Wendy Higashide, Chrissie Lee, Shahrooz Rabizadeh
  • Patent number: 9708631
    Abstract: An improved process for alcohol production includes microbial fermentation using a genetically modified microorganism to produce substantial quantities of aldehydes that are stripped from the fermentation medium and condensed. So produced aldehydes are converted in an ex vivo process to corresponding alcohols.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: July 18, 2017
    Assignee: Easel Biotechnologies, LLC
    Inventors: Wendy M. Higashide, Kwang Myung Cho, Shahrooz Rabizadeh
  • Patent number: 9512450
    Abstract: Systems, methods, and metabolically engineered microorganisms are contemplated in which low molecular weight gases, and especially methane and syngas are used as a carbon source, and in which CO2 or formaldehyde and reduction equivalents are generated for use in in vivo production of the value products.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: December 6, 2016
    Assignee: Easel Biotechnologies, LLC
    Inventors: Yi-Xin Huo, Lars Erik Ulf Rohlin, Shahrooz Rabizadeh
  • Publication number: 20160348086
    Abstract: Genetically engineered cells and methods are presented that allow for the production of various value products from CO2. Contemplated cells have a CBB cycle that is genetically modified such that two molecules of CO2 fixed in the CBB cycle can be withdrawn from the modified CBB cycle as a single C2 compound. In contemplated aspects a CBB cycle includes an enzymatic activity that generates the single C2 compound from a compound of the CBB cycle, while further modifications to the CBB cycle will not introduce additional recombinant enzymatic activity/activities outside the already existing catalytic activities in the CBB cycle.
    Type: Application
    Filed: January 30, 2015
    Publication date: December 1, 2016
    Applicant: Easel Biotechnologies, LLC
    Inventors: Yi-Xin Huo, Benjamin Schilling, Shahrooz Rabizadeh
  • Patent number: 9206443
    Abstract: An improved process for alcohol production includes microbial fermentation using a genetically modified microorganism to produce substantial quantities of aldehydes that are stripped from the fermentation medium and condensed. So produced aldehydes are converted in an ex vivo process to corresponding alcohols.
    Type: Grant
    Filed: March 14, 2012
    Date of Patent: December 8, 2015
    Assignee: Easel Biotechnologies, LLC
    Inventors: Wendy M. Higashide, Kwang Myung Cho, Shahrooz Rabizadeh
  • Publication number: 20140011231
    Abstract: An improved process for alcohol production includes microbial fermentation using a genetically modified microorganism to produce substantial quantities of aldehydes that are stripped from the fermentation medium and condensed. So produced aldehydes are converted in an ex vivo process to corresponding alcohols.
    Type: Application
    Filed: March 14, 2012
    Publication date: January 9, 2014
    Applicant: Easel Biotechnologies, LLC
    Inventors: Wendy M. Higashide, Kwang Myung Cho, Shahrooz Rabizadeh