Patents Assigned to East China University of Science and Technology
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Patent number: 11971376Abstract: An experimental technology for detecting a hydrogen bond based on an ssNMR technology includes: (1) exciting a 1H nucleus of an RNA sample with a ?/2 pulse; (2) applying two ? pulses every half rotation period on an X nucleus of the RNA sample; (3) applying a ? pulse on the 1H nucleus of the RNA sample; (4) applying two ? pulses every half rotation period on the X nucleus of the RNA sample; (5) applying a 90° pulse on 1H and X atoms of the RNA sample; r a chemical shift of X in indirect dimension; (7) applying the 90° pulse on the 1H and X nuclei of the RNA sample; (8) repeating steps 2, 3, and 4; and (9) collecting the 1H signal in direct dimension; where X is selected from the group consisting of 15N and 13C.Type: GrantFiled: September 23, 2022Date of Patent: April 30, 2024Assignee: East China University of Science and TechnologyInventors: Shenlin Wang, Sha Zhao
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Patent number: 11965070Abstract: The disclosure relates to the field of electronic materials, and in particular to a composite film of fluorinated polybenzoxazole (6FPBO) and triple-shelled mesoporous silica hollow spheres, and to its preparation and use. The composite film comprises fluorinated polybenzoxazole as a matrix and amino-functionalized triple-shelled mesoporous silica hollow spheres which are dispersed in the fluorinated polybenzoxazole matrix. A mass ratio of (amino-functionalized triple-shelled mesoporous silica hollow spheres)/(fluorinated polybenzoxazole) is 1/100 to 5/100. The composite film has excellent thermal stability and a lower dielectric constant.Type: GrantFiled: November 1, 2021Date of Patent: April 23, 2024Assignee: East China University of Science and TechnologyInventors: Qixin Zhuang, Zhe Zhang, Xiaoyun Liu, Jian Xu, Wentao Wang, Zeyang Wu, Xiaohan Wu, Lihui Li
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Patent number: 11963453Abstract: A piezoelectric sensor is provided. The piezoelectric sensor comprises a first base, a first conductive layer adjacent to the first base, a second base, a second conductive layer adjacent to the second base; and a first structure between the first conductive layer and the second conductive layer. The first structure comprises a first layer with a first carbon-based material and a plurality of second structures with piezoelectricity. Each of the plurality of second structures comprises a second layer with a second carbon-based material and a third layer adjacent to the second layer. The third layer comprises a material of two-dimensional crystals of unconventional stoichiometries such as Na2Cl crystals.Type: GrantFiled: August 23, 2023Date of Patent: April 16, 2024Assignees: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY, NINGBO UNIVERSITYInventors: Haiping Fang, Liang Chen, Chaofeng Lv
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Patent number: 11952540Abstract: A method and apparatus for hydrocracking mineralized refuse pyrolysis oil. The method may use the following steps: (a) crushing and pyrolyzing mineralized refuse to obtain arene and alkane precursor biomass oil; (b) hydrogenating the arene and alkane precursor biomass oil obtained in step (a), and separating the obtained hydrocrackate to obtain arene and alkane; and (c) purifying, recovering and optimizing the arene and alkane obtained in step (b), and performing deep processing to produce naphtha, jet fuel, light diesel oil, and heavy diesel oil.Type: GrantFiled: June 16, 2020Date of Patent: April 9, 2024Assignee: East China University of Science and TechnologyInventors: Yulong Chang, Hualin Wang, Xia Jiang, Jianping Li, Jingyi Zhu, Pengbo Fu, Wei Yuan
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Publication number: 20240104482Abstract: An anti-fatigue and safety control method for ultra-long life service structures under extreme environment, comprising: judge the fatigue fracture mode in the long life stage of the service structure; according to the interaction principle of defect-matrix, obtain the internal defect induced fatigue cracking mechanism in ultra-high cycle regime under the service environment; considering the environmental factors, clarify the internal defect-matrix-environment interaction mechanism under service conditions and obtain the environmental weakening coefficient; considering the environmental factors, establish a fatigue life prediction model based on defect-load-life correlation under service conditions in ultra-high cycle regime; the process parameters of material metallurgy and manufacturing, design parameters of structural strength, structural service stress and environmental parameters are regulated based on the concept of integrated design/manufacturing.Type: ApplicationFiled: July 27, 2023Publication date: March 28, 2024Applicant: East China University of Science and TechnologyInventors: Mingliang ZHU, Fuzhen XUAN, Gang ZHU, Shan-Tung TU
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Publication number: 20240101974Abstract: Embodiments of the present disclosure relate to a D-amino acid oxidase mutant and application in preparing L-glufosinate thereof. The D-amino acid oxidase mutant has an amino acid substitution at at least one of position 62 and position 226 of an amino acid sequence of the D-amino acid oxidase mutant when compared to an amino acid sequence of a D-amino acid oxidase as set forth in SEQ ID NO. 1, the position 62 and position 226 being defined with reference to SEQ ID NO. 1, and the amino acid sequence of the D-amino acid oxidase mutant having at least 90% identity to SEQ ID NO. 1.Type: ApplicationFiled: September 18, 2023Publication date: March 28, 2024Applicants: YONGNONG BIOSCIENCES CO., LTD., EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY, NINGXIA YONGNONG BIOSCIENCES CO., LTD.Inventors: Dongzhi WEI, Hualei WANG, Chengjun WU, Qinghai LIU, Jian ZHANG, Zhonghua LUO, Changlei ZHANG
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Patent number: 11918992Abstract: The present application discloses a multi-region plasma shell-and-tube reactor comprising a shell body. At least two reaction regions are provided inside the shell body, and a horizontal separation panel is provided between any two adjacent reaction regions, used to separate the two and passing through the tubes. A central hole is provided in the center of any horizontal separation panel, and at least one auxiliary hole distributed around the central axis of the central hole is provided in any horizontal separation panel so as to cooperate with the central hole to cause a vortex state to be formed in a reaction region.Type: GrantFiled: November 23, 2020Date of Patent: March 5, 2024Assignees: ZHEJIANG WYNCA CHEMICAL INDUSTRY GROUP CO., LTD, EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Zhenmin Cheng, Shengbao Jiang, Shenluan Yu, Shuguang Zhou, Minhai Tu, Long Qin, Zhichao Jin, Zibin Huang, Meichen Chen, Peiqing Yuan
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Publication number: 20240058773Abstract: The invention provides a device for enhancing liquid-liquid emulsification. The device includes a jet part and a mixing part connected to the jet part. The jet part includes a feed tee for feeding major and dispersed phases, wherein the feed tee includes a first port, a second port, and a third port. The first port is used for feeding the major phase, and the second port is equipped with an ejector for feeding the dispersed phase. The ejector consists of an ejector housing and an ejector inlet section, as well as a spiral structure, a flow-guided structure, and an ejector pin structure that are connected sequentially. The mixing part includes a mixer comprising a cylindrical mixer shell, a mixer inlet section, a mixer outlet section, as well as a spiral section, a cavity section, and a variable diameter section for enhancing emulsion breakup and dispersion. A method for enhancing liquid-liquid emulsification is also disclosed.Type: ApplicationFiled: March 25, 2021Publication date: February 22, 2024Applicant: East China University of Science and TechnologyInventors: Hao LU, Qiang YANG, Yudong LI, Yiqian LIU, Pinyi DAI, Shihan WU
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Patent number: 11904423Abstract: Provided is a bilateral ultrasonic rolling processing track coordination method for a blade surface, the method comprising: step S1, performing layering processing on a blade to acquire a contour curve of “A”-shaped and “n”-shaped blade edges of a blade model at different heights; step S2: determining the endpoints of a blade processing track; and step S3: planning the thickness and the rotation angle of the blade, comprising: step S31, solving a main direction angle ?main of the contour curve; step S32, solving the thickness d of the blade; step S33, solving a rotation angle required by blade processing when the blade edge is “A”-shaped; and step S34, solving the rotation angle required by blade processing when the blade edge is “n”-shaped. According to the method, blade deformation generated by an ultrasonic rolling force is reduced, the processing efficiency is improved, and the blade processing precision is also improved.Type: GrantFiled: May 20, 2020Date of Patent: February 20, 2024Assignee: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Xiancheng Zhang, Kaiming Zhang, Shulei Yao, Shuang Liu, Feng Cheng, Shantung Tu
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Patent number: 11905369Abstract: The present invention relates to a strong base-initiated N-carboxyanhydride rapid ring-opening polymerisation method. Specifically, the method comprises steps of: performing a polymerisation reaction with one or more amino acid N-carboxyanhydride monomers in an organic solvent in the presence of an initiator, so as to form an amino acid polymer, wherein the initiator is selected from the following group: LiHMDS, NaHMDS, KHMDS, or a combination thereof. The method significantly increases the speed of traditional NCA polymerisation and prepares a long-chain polymer, and the prepared amino acid polymer may be used as an anti-bacterial material, an anti-tumour material, a tissue engineering scaffold or a self-assembling material.Type: GrantFiled: June 13, 2019Date of Patent: February 20, 2024Assignee: East China University of Science and TechnologyInventors: Runhui Liu, Yueming Wu
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Patent number: 11857897Abstract: The present disclosure relates to a gas cooling-scrubbing apparatus and an associated method. There is provided a gas cooling-scrubbing apparatus, comprising: a cyclone jet scrubbing unit, a spray scrubbing unit, a filtering spray unit, and a coalescing dehydration unit, wherein the cyclone jet scrubbing unit comprises a cyclone jet scrubbing monopipe (2), a cyclone jet cooling water pipe (15), a cyclone jet pipe plate (14) and a cyclone jet overflow pipe (13); wherein the spray scrubbing unit comprises a spray filtering pipe (3), a spray pipe plate (11), a spray overflow pipe (12), a scrubbing nozzle (9) and a scrubbing nozzle water pipe (10); wherein the filtering spray unit comprises a filtering bed (4), a spray head (7) and a spray water pipe (8); and wherein the coalescing dehydration unit comprises a coalescing bed (5). There is also provided a gas cooling-scrubbing method.Type: GrantFiled: January 17, 2022Date of Patent: January 2, 2024Assignee: East China University of Science and TechnologyInventors: Zhishan Bai, Fuwei Lv, Xiao Dong
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Publication number: 20230414837Abstract: Disclosed are a polypeptide polymer-doped bone marrow cavity filler and the use thereof in the treatment of osteomyelitis, wherein the polypeptide polymer is used for being doped in a bone marrow cavity filler or preparing a bone marrow cavity filling antibacterial material for treating osteomyelitis, has efficient antibacterial activity on common staphylococcus aureus, etc., in osteomyelitis, is not easy to induce bacteria to generate drug resistance, has good biocompatibility in environments such as bone marrow and blood, has good stability, and still keeps activity after forming heat release and even the autoclaving of bone cement.Type: ApplicationFiled: November 16, 2021Publication date: December 28, 2023Applicants: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY, SHANGHAI FIRST PEOPLE'S HOSPITALInventors: Runhui Liu, Haodong Lin, Yueming Wu
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Patent number: 11827990Abstract: A dual-membrane on-line generator for an acid or alkali solution is provided, including an upper electrolytic cell body (3), a middle electrolytic cell body (4) and a lower electrolytic cell body (5) which are clamped by an upper fastening steel plate (1) and a lower fastening steel plate (2), an upper regeneration liquid channel (A), a middle eluent channel (B) and a lower regeneration liquid channel (C) being provided on the middle electrolytic cell body (4).Type: GrantFiled: June 14, 2019Date of Patent: November 28, 2023Assignees: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY, SHIMADZU (CHINA) CO., LTD.Inventors: Bingcheng Yang, Feifang Zhang, Yifei Lu, Liting Zhou, Shujun Huang
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Publication number: 20230339785Abstract: The present disclosure relates to a deep purification device and method for methanol-to-olefin washing water. Provided is a deep purification device for methanol-to-olefin washing water, comprising: a quench tower (1-1), a water washing tower (1-2) connected to an outlet at the top of the quench tower (1-1), a boiling bed separator (1-3) having the top thereof connected to the bottom of the water washing tower (1-2), a fiber coalescer (1-4) connected to the bottom of the boiling bed separator (1-3), and a buffer settling tank (1-5) connected to the sidewall of the boiling bed separator (1-3) at a position near the top. Further provided is a deep purification method for methanol-to-olefin washing water.Type: ApplicationFiled: September 17, 2020Publication date: October 26, 2023Applicants: East China University of Science and Technology, Shanghai Huachang Environmental Protection Co., Ltd, Shaanxi Petroleum Yanan Energy Chemical Industry Limited Liability CompanyInventors: Jianqi CHEN, Hualin WANG, Wenjie LV, Ting LEI, Liang CHEN, Tianxiang WANG, Xiaobin XUE, Bing LIU, Xin CUI, Weichi SANG, Jinsong WANG, Jinlan FENG, Hongpeng MA, Wei YUAN, Bin HU, Yujie JI
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Publication number: 20230324373Abstract: Disclosed in the present invention are a pyruvic acid optical probe, a preparation method therefor, and an application thereof. One aspect of the present invention is the disclosure of an optical probe, which includes a pyruvic acid-sensitive polypeptide and an optically active polypeptide, wherein the optically active polypeptide is located within the sequence of the pyruvic acid-sensitive polypeptide. The present invention also discloses a preparation method for the probe and an application of said probe in pyruvic acid measurement.Type: ApplicationFiled: February 9, 2021Publication date: October 12, 2023Applicant: East China University of Science and TechnologyInventors: Yi Yang, Yuzheng Zhao, Xie Li, Zeyi Zhang, Xiuze Zhang, Li Huang
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Patent number: 11766665Abstract: Disclosed is a method for efficiently synthesizing primary amines, which comprises using carbonyl compounds or alcohol compounds as reaction substrate, liquid ammonia or alcohol solutions of ammonia as nitrogen source, and hydrogen as hydrogen source, and reacting in reaction medium catalyzed by a cobalt-based catalyst to obtain the primary amines. Due to high catalytic activity, the method can realize the reductive amination of carbonyl compounds and the hydrogen-borrowing amination of alcohol compounds at low temperatures in a short time to obtain the primary amines with high yield, and is applicable to a wide range of substrates. The obtained primary amines can be used as raw materials with high extra value for producing polymers, medicines, dyes and surfactants. Further, the cobalt-based catalyst has a good industrial application prospect because it is magnetic which can facilitate separation and recycling of the catalyst.Type: GrantFiled: December 28, 2021Date of Patent: September 26, 2023Assignee: East China University of Science and TechnologyInventors: Yanqin Wang, Wanjun Guo, Shuang Xiang, Xiaohui Liu, Yong Guo
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Publication number: 20230296616Abstract: Provided is an arginine fluorescent probe, comprising a polypeptide B that responds to arginine and a fluorescent protein A that expresses arginine; the fluorescent protein A is inserted into the polypeptide B, B is divided into an upper structural part and a lower structural part, B1 and B2, and a probe structure represented by the formula B1-A-B2 is formed; optimized mutants are likewise obtained by truncation and site-directed mutagenesis at different positions, and specific binding of the polypeptide B and arginine leads to a change in the fluorescence signal of the fluorescent protein A; and the polypeptide B is an arginine binding protein or a mutant thereof.Type: ApplicationFiled: February 9, 2021Publication date: September 21, 2023Applicant: East China University of Science and TechnologyInventors: Yi Yang, Yuzheng Zhao, Rui Li, Yejun Zou, Li Huang, Xie Li, Kun Jiang
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Publication number: 20230296617Abstract: Disclosed is a tryptophan optical probe, a preparation method therefor and the use thereof. Disclosed is an optical probe, comprising a tryptophan-sensitive polypeptide or a functional variant thereof and an optically active polypeptide or a functional variant thereof, wherein the optically active polypeptide or the functional variant thereof is located in the sequence of the tryptophan-sensitive polypeptide or the functional variant thereof. Furthermore, disclosed are a method for preparing the above-mentioned probe and the use thereof in the detection of tryptophan.Type: ApplicationFiled: February 9, 2021Publication date: September 21, 2023Applicant: East China University of Science and TechnologyInventors: Yi Yang, Yuzheng Zhao, Chenxia Zhang, Li Huang, Yejun Zou, Xie Li, Shuning Liu
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Publication number: 20230203506Abstract: An optical probe, comprising a lactic acid-sensitive polypeptide or a functional variant thereof and an optically active polypeptide or a functional variant thereof; the optically active polypeptide or the functional variant thereof is located in the sequence of the lactic acid-sensitive polypeptide or the functional variant thereof. A preparation method for the described probe and an application thereof in the detection of lactic acid.Type: ApplicationFiled: December 21, 2020Publication date: June 29, 2023Applicant: East China University of Science and TechnologyInventors: Yi Yang, Yuzheng Zhao, Xie Li, Xiuze Zhang, Li Huang
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Publication number: 20230102416Abstract: Disclosed is a method for efficiently synthesizing primary amines, which comprises using carbonyl compounds or alcohol compounds as reaction substrate, liquid ammonia or alcohol solutions of ammonia as nitrogen source, and hydrogen as hydrogen source, and reacting in reaction medium catalyzed by a cobalt-based catalyst to obtain the primary amines. Due to high catalytic activity, the method can realize the reductive amination of carbonyl compounds and the hydrogen-borrowing amination of alcohol compounds at low temperatures in a short time to obtain the primary amines with high yield, and is applicable to a wide range of substrates. The obtained primary amines can be used as raw materials with high extra value for producing polymers, medicines, dyes and surfactants. Further, the cobalt-based catalyst has a good industrial application prospect because it is magnetic which can facilitate separation and recycling of the catalyst.Type: ApplicationFiled: December 28, 2021Publication date: March 30, 2023Applicant: East China University of Science and TechnologyInventors: Yanqin WANG, Wanjun GUO, Shuang XIANG, Xiaohui LIU, Yong GUO