Patents Assigned to Eastern Kentucky University
  • Patent number: 11197888
    Abstract: The conjugation of luteinizing hormone-releasing hormone (LHRH) with activated cisplatin using a malonate linker gives rise to a new Platinum-LHRH conjugate that effectively targets tumor cells that express the LHRH receptor. The Pt-LHRH conjugate may be used in a method for killing or inhibiting the growth of a tumor cell, especially in late state, highly invasive and aggressive stage IV tumors and in reoccurring tumors.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: December 14, 2021
    Assignee: Eastern Kentucky University
    Inventors: Margaret Ndinguri, Lindsay Calderon
  • Publication number: 20190111077
    Abstract: The conjugation of luteinizing hormone-releasing hormone (LHRH) with activated cisplatin using a malonate linker gives rise to a new Platinum-LHRH conjugate that effectively targets tumor cells that express the LHRH receptor. The Pt-LHRH conjugate may be used in a method for killing or inhibiting the growth of a tumor cell, especially in late state, highly invasive and aggressive stage IV tumors and in reoccurring tumors.
    Type: Application
    Filed: October 12, 2018
    Publication date: April 18, 2019
    Applicant: Eastern Kentucky University
    Inventors: Margaret Ndinguri, Lindsay Calderon
  • Patent number: 10130717
    Abstract: The conjugation of luteinizing hormone-releasing hormone (LHRH) with activated cisplatin using a malonate linker gives rise to a new Platinum-LHRH conjugate that effectively targets tumor cells that express the LHRH receptor. The Pt-LHRH conjugate may be used in a method for killing or inhibiting the growth of a tumor cell, especially in late state, highly invasive and aggressive stage IV tumors and in reoccurring tumors.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: November 20, 2018
    Assignee: Eastern Kentucky University
    Inventors: Margaret Ndinguri, Lindsay Calderon
  • Patent number: 9784571
    Abstract: To obtain a three-dimensional virtual reconstruction of a workpiece the workpiece is positioned on a display screen between the display screen and at least one imager wherein the imager acquires multiple images of the workpiece while (a) multiple light stripes are displayed and swept in a first directional orientation across the display screen, (b) multiple light stripes are displayed and swept in at least one second directional orientation across the display screen, and (c) multiple images for each position of the multiple light stripes at different exposure times are captured. From the multiple images, a difference caused by the workpiece in a width and a profile of the multiple light stripes is determined. That difference is used to calculate a depth value (z) of the workpiece at each imager pixel position (x, y). The calculated depth value is used to reconstruct a surface shape of the workpiece.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: October 10, 2017
    Assignee: Eastern Kentucky University
    Inventor: George V. Landon
  • Publication number: 20170157263
    Abstract: The conjugation of luteinizing hormone-releasing hormone (LHRH) with activated cisplatin using a malonate linker gives rise to a new Platinum-LHRH conjugate that effectively targets tumor cells that express the LHRH receptor. The Pt-LHRH conjugate may be used in a method for killing or inhibiting the growth of a tumor cell, especially in late state, highly invasive and aggressive stage IV tumors and in reoccurring tumors.
    Type: Application
    Filed: December 2, 2016
    Publication date: June 8, 2017
    Applicant: Eastern Kentucky University
    Inventors: Margaret Ndinguri, Lindsay Calderon
  • Publication number: 20140340485
    Abstract: Methods and systems for three-dimensional virtual reconstruction of a workpiece surface are provided. A workpiece is positioned on a display screen between the display screen and at least one imager. The imager acquires multiple images of the workpiece while (a) multiple light stripes are displayed and swept in a first directional orientation across the display screen, (b) multiple light stripes are displayed and swept in at least one second directional orientation across the display screen, and (c) multiple images for each position of the multiple light stripes at different exposure times are captured. From the multiple images, a difference caused by the workpiece in a width and a profile of the multiple light stripes is determined. That difference is used to calculate a depth value (z) of the workpiece at each imager pixel position (x, y). The calculated depth value is used to reconstruct a surface shape of the workpiece.
    Type: Application
    Filed: May 15, 2014
    Publication date: November 20, 2014
    Applicant: Eastern Kentucky University
    Inventor: George V. Landon