Abstract: Disclosed is a gene encoding a mutated lactoferricin peptide and an E. coli cell transformed with the same, wherein the mutated lactoferricin peptide has substitutions at the 7th and 10th amino acid residues of the wildtype bovine lactoferricin. The gene of the present invention can be expressed in E. coli at high efficiency, and the expressed mutated lactoferricin peptide can be purified at high yield, thus making its mass production possible.
Type:
Grant
Filed:
November 30, 2002
Date of Patent:
March 6, 2007
Assignee:
Easy Bio System, Inc.
Inventors:
Ha-Kun Kim, Dae-Kyung Kang, Ju-Hoon Lee