Abstract: Systems and methods are described that provide for targeted distribution of messages through communication networks, such as the Internet, in private and confidential environments. Messages, such as advertisements, can be stored in a message database. In a secure environment, consumer profiles, such as medical records, can be mined to identify target consumers for a given message. Messages can be retrieved from the message database, encrypted, and conveyed to the identified target consumers without inappropriately revealing or disclosing private or confidential consumer data.