Abstract: A method for making a laminated chip includes: (a) forming a first conductive layer on a substrate; (b) forming an insulating layer on the first conductive layer opposite to the substrate; (c) bombarding the insulating layer using an electron beam to form a plurality of holes that expose the first conductive layer; and (d) forming a second conductive layer on the insulating layer such that a part of the second conductive layer extends into the holes to electrically connect to the first conductive layer.
Abstract: Real time biofilm monitoring systems are provided. Said systems comprise single or multiple fiber-optic probes detecting wavelength-specific fluorescence from biomarkers of fouling organisms; a compact optoelectronic interface and data acquisition system interfaced with said probes, wherein said probe or probes are bifurcated and contain at least one excitation and at least one emission filter permitting the simultaneous resolution of multiple biomarkers.
Type:
Grant
Filed:
January 13, 2004
Date of Patent:
March 13, 2007
Assignee:
Echo Technologies, Inc.
Inventors:
Mary Elizabeth Tabacco, Marc W Mittelman, J. Anthony Schanzie
Abstract: Real time biofilm monitoring systems are provided. Said systems comprise single or multiple fiber-optic probes detecting wavelength-specific fluorescence from biomarkers of fouling organisms; a compact optoelectronic interface and data acquisition system interfaced with said probes, wherein said probe or probes are bifurcated and contain at least one excitation and at least one emission filter permitting the simultaneous resolution of multiple biomarkers.
Type:
Application
Filed:
January 13, 2004
Publication date:
July 14, 2005
Applicant:
ECHO Technologies, Inc.
Inventors:
Mary Tabacco, Marc Mittelman, J. Schanzie
Abstract: Bacterial spores can be rapidly and sensitively detected and quantified based upon molecular recognition of unique chemicals in the spore coat. Spores can be detected and assayed based upon the calcium concentration in bacterial spore coats using the calcium which is unique to the bacterial spores. Since spores contain a high concentration of calcium relative to other biological materials, fluorescent calcium-sensitive indicators are used to detect Ca+2 displaced from the spore case or free in solution or from the aerosol phase. Visibly excitable fluorescent dyes provide a sensitive and selective means to monitor changes in spore concentration and avoid difficulties associated with laser or UV-excitation.
Abstract: Sensors for detecting microorganisms in gases, liquids, and aerosols are provided which include molecular receptors to interact with the microorganisms, polymeric membranes containing luminescent reagents, optional non-drying membrane additives, an optical substrate as a sensor support, an optional conformable optical substrate or rotating film to refresh the sensor chemistry, and means for detecting the signal from the sensor. Optical sign can be enhanced by immobilizing biocidal compounds in the sensing membrane, immobilizing metal colloids in the sensing membrane, or immobilizing sol-gel coated colloidal particles in the sensing membrane.
Type:
Grant
Filed:
July 27, 2000
Date of Patent:
November 26, 2002
Assignee:
Echo Technologies
Inventors:
Mary Beth Tabacco, Han Chuang, John Anthony Schanzle