Abstract: Real time biofilm monitoring systems are provided. Said systems comprise single or multiple fiber-optic probes detecting wavelength-specific fluorescence from biomarkers of fouling organisms; a compact optoelectronic interface and data acquisition system interfaced with said probes, wherein said probe or probes are bifurcated and contain at least one excitation and at least one emission filter permitting the simultaneous resolution of multiple biomarkers.
Type:
Grant
Filed:
January 13, 2004
Date of Patent:
March 13, 2007
Assignee:
Echo Technologies, Inc.
Inventors:
Mary Elizabeth Tabacco, Marc W Mittelman, J. Anthony Schanzie
Abstract: Real time biofilm monitoring systems are provided. Said systems comprise single or multiple fiber-optic probes detecting wavelength-specific fluorescence from biomarkers of fouling organisms; a compact optoelectronic interface and data acquisition system interfaced with said probes, wherein said probe or probes are bifurcated and contain at least one excitation and at least one emission filter permitting the simultaneous resolution of multiple biomarkers.
Type:
Application
Filed:
January 13, 2004
Publication date:
July 14, 2005
Applicant:
ECHO Technologies, Inc.
Inventors:
Mary Tabacco, Marc Mittelman, J. Schanzie
Abstract: Bacteria in fluid systems are identified by using a fluorescently labeled virus as a molecular recognition element for bacteria. The virus, or bacteriophage, are optically encoded with fluorescent reporter molecules to allow detection and quantitation of the phage and the host/phage complex. Biosensors are provided in which the molecular recognition element is immobilized on a substrate.
Type:
Application
Filed:
March 24, 2003
Publication date:
September 30, 2004
Applicant:
ECHO TECHNOLOGIES, INC.
Inventors:
Mary Beth Tabacco, Xiaohua Qian, Jaimie Russo
Abstract: Bacterial spores can be rapidly and sensitively detected and quantified based upon molecular recognition of unique chemicals in the spore coat. Spores can be detected and assayed based upon the calcium concentration in bacterial spore coats using the calcium which is unique to the bacterial spores. Since spores contain a high concentration of calcium relative to other biological materials, fluorescent calcium-sensitive indicators are used to detect Ca+2 displaced from the spore case or free in solution or from the aerosol phase. Visibly excitable fluorescent dyes provide a sensitive and selective means to monitor changes in spore concentration and avoid difficulties associated with laser or UV-excitation.