Abstract: Compositions comprising peptides that are capable of binding a metal are disclosed. Such compositions can be used for binding metal in a variety of contexts and environments. In various embodiments, peptides are used for antioxidant activity, anti-inflammatory activity, anti-pain therapy, as chemical reagents, and/or as superoxide dismutase mimics.
Type:
Grant
Filed:
May 30, 2013
Date of Patent:
November 17, 2015
Assignees:
UNIVERSITY OF KANSAS, ECHOGEN, INC.
Inventors:
Jennifer Ann Stowell Laurence, Mary Elizabeth Krause, Timothy A. Jackson, Amanda Michelle Glass, George Laurence
Abstract: Compositions comprising peptides that are capable of binding a metal in a square planar orientation, a square pyramidal orientation, or both, are disclosed. Such compositions can be used for binding and releasing a metal in a variety of contexts and environments, such as the treatment of cancer.
Type:
Application
Filed:
July 18, 2013
Publication date:
February 6, 2014
Applicants:
Echogen, Inc., University of Kansas
Inventors:
Jennifer Ann Stowell Laurence, Mary Elizabeth Krause, George Laurence
Abstract: Compositions comprising peptides that are capable of binding a metal are disclosed. Such compositions can be used for binding metal in a variety of contexts and environments. In various embodiments, peptides are used for antioxidant activity, anti-inflammatory activity, anti-pain therapy, as chemical reagents, and/or as superoxide dismutase mimics.
Type:
Application
Filed:
May 30, 2013
Publication date:
December 12, 2013
Applicants:
Echogen, Inc., University of Kansas
Inventors:
Jennifer Ann Stowell Laurence, Mary Elizabeth Krause, Timothy A. Jackson, Amanda Michelle Glass, George Laurence
Abstract: Compositions comprising certain tripeptides which are capable of binding a metal in a square planar orientation, a square pyramidal orientation, or both, are disclosed in processes for modulating tagged peptides or proteins. Such compositions and processes may be used for site-specific chiral inversion of amino acids, site-specific peptide cleavage, and protein purification, among other uses.
Type:
Application
Filed:
January 13, 2012
Publication date:
January 17, 2013
Applicants:
Echogen, Inc., University of Kansas
Inventors:
Jennifer Ann Stowell Laurence, Mary Elizabeth Krause, Timothy A. Jackson, George Laurence