Abstract: The present invention relates to a new method for repairing human or animal tissues such as cartilage, meniscus, ligament, tendon, bone, skin, cornea, periodontal tissues, abscesses, resected tumors, and ulcers. The method comprises the step of introducing into the tissue a temperature-dependent polymer gel composition such that the composition adhere to the tissue and promote support for cell proliferation for repairing the tissue. Other than a polymer, the composition preferably comprises a blood component such as whole blood, processed blood, venous blood, arterial blood, blood from bone, blood from bone-marrow, bone marrow, umbilical cord blood, placenta blood, erythrocytes, leukocytes, monocytes, platelets, fibrinogen, thrombin and platelet rich plasma. The present invention also relates to a new composition to be used with the method of the present invention.

Abstract: The present invention relates to a system and a method for monitoring body movement, in particular but not exclusively for evaluating the falling risk and/or for monitoring sitting, standing, lying, walking and running periods. The system is characterized by the fact that it comprises means for determining the time of postural transition.

Abstract: A new noninvasive approach for intraocular pressure (IOP) measurement allowing continuous monitoring over prolonged periods, regardless of patient's position and activities. The key element of this measurement method is a soft contact lens (1) including at least one strain gage (2) longitudinally arranged around the center of the contact lens and capable of measuring precisely spherical deformations of the eyeball induced by the changes in IOP. This information is transmitted with wires or (preferably) wirelessly in real time to an external recording system (14). The system is placed in the same way as a normal corrective contact lens, no anesthesia is required and patient vision remains almost completely unimpaired.

Abstract: The invention provides methods for the preparation of multiblock copolymers, dispersions of multiblock copolymers, vesicles and micelles containing multiblock copolymers, and oxidative degradation products of multiblock copolymers.

Abstract: A device for directional and wavelength-selective optical coupling formed in a photonic crystal (12) and comprising two parallel waveguides (14, 16) separated by a coupling zone (18) enabling a particular frequency to be extracted from a signal (30) injected in fundamental mode into one of the waveguide (14) and to recover said frequency at the outlet (34) of the other waveguide (16), extraction and injection being performed by coupling between fundamental and high order modes in each waveguide.

Abstract: An integrated imager circuit comprising a monolithic array of single photon avalanche diodes (SPADs) for capturing an image of a scene when said scene is hit by an optical pulse, said array comprising: a plurality of SPADs connected to 2D readout circuits determines the intensity of the light reflected by said scene by counting the number of photons received by said SPADs during a period of time, a plurality of SPADs connected to 3D readout circuits determines the distance to said scene by determining the elapsed time between the emission of each pulse and reception of the corresponding reflected photons.

Abstract: The present invention relates to an apparatus and a method of fabricating the apparatus for dispensing a sample for subsequent analysis by mass spectrometry. The apparatus comprises a polymer substrate (1), in which a covered microchannel (3) has been etched, a wall of the microchannel comprising an electrically conductive material (2) for applying a voltage allowing the sample to be sprayed into a mass spectrometer from the open end (4) of the microchannel. The present application also discloses various applications of the apparatus.

Abstract: An intravascular dilator includes a central body acting as deflector o the blood flow to increase the value of shear stress to the artery wall. Flexible spires soldered to the deflector are radially extensible from a first diameter substantially equal to the deflector diameter to a second diameter greater than the artery diameter, the spires rest against the artery internal wall in operative position.

Abstract: Endosseous implant to be applied to human or animal bone, said implant having a surface made from a selected metal or a selected metal alloy or a ceramic, whereby said metal resp. metal alloy is selected from chromium, niobium, tantalum, vanadium, zirconium, aluminium, cobalt, nickel, stainless steels or an alloy thereof, said surface having a smooth or rough texture, characterized in that said surface has been treated with at least one pharmaceutically acceptable organic compound carrying at least one phosphonic acid group or a derivative thereof preferably a pharmaceutically acceptable salt or ester or amid thereof and method for producing said implant.

Abstract: The present invention provides methods and apparatus for locally patterning surfaces. In one such method, an oxidizable thioether is adsorbed onto a conductive surface. The surface is then contacted with a fluid medium. A conducting stamp is then brought into contact with the fluid medium above the thioether-coated surface. Next, a potential is applied between the stamp and the surface. It is expected that the charge will be transferred through the medium to the coated surface along a shortest distance path, thereby locally oxidizing the thioether and effectively creating a negative patterned image of the conducting stamp on the surface. Remaining adsorbed thioether may then be used as a mask for standard etching or material addition procedures.

Abstract: The invention relates to a non-linear optical filter capable of transmitting an electromagnetic pulse with a duration of less than about 1 picosecond, provided with means for generating an electromagnetic field E with a linear polarization from this pulse, and with a crystal C1 of cubic geometry capable of generating an electromagnetic field E?1 from E with a linear polarization orthogonal to that of E. It comprises means for generating at least one other electromagnetic field E?2 capable of producing constructive interferences with the electromagnetic field E?1.

Abstract: Supported photooxidation catalysts containing a metal oxide or metal ion as catalyst which is fixed to the support by means of carboxylate moieties are an alternative to existing such catalysts, particularly if low cost supports such as organic polymers, particularly polyethylene, are used. The supported photocatalysts can be used in mineralisation of organic pollutants in both liquids and gases and show reduced leaching of the catalyst and good resistance towards reactive oxygen species generated during the degradation process.

Abstract: The application describes ligands for binding targets, the ligands preferably including peptides having at least one sulfated or sulfonated amino acid. The ligand preferably specifically binds to heparin binding sites of biomolecules. Compositions, systems, and methods for making and using the ligands are described.

Abstract: This invention discloses new methods, security devices and apparatuses for authenticating documents and valuable articles which may be applied to any support, including transparent synthetic materials and traditional opaque materials such as paper. The invention relates to moire intensity profiles which occur in the superposition of specially designed random structures. By using specially designed random basic screen and random master screen, where at least the basic screen is comprised in the document, a moire intensity profile of a chosen shape becomes visible in their superposition, thereby allowing the authentication of the document. An important advantage of the present invention is that it can be incorporated into the standard document printing process, so that it offers high security at the same cost as standard state of the art document production.

Abstract: The invention provides a method and apparatus for the reproduction of color images by multi-color dithering. Multi-color dithering is an extension of bi-level dithering for halftoning an input image using as primary colors an arbitrary number of inks. The inks may comprise standard inks or non-standard inks such as non-process color inks, opaque inks, metallic inks, variable color inks and fluorescent inks. Multi-color dithering provides a solution for creating artistic multi-color dithered images, whose screen elements are made of artistic color screen shapes such as micro-letters, symbols and ornaments. When printed at high resolution and at high registration accuracy, multi-color dithering using large dither arrays incorporating artistic dither shapes provides an effective solution for preventing counterfeiting. The use of non-standard inks offers additional protection. Multi-color dithering also offers a solution for printers requiring that all inks are printed side by side, without overlaps.

Abstract: A solid state p-n heterojunction comprising an electron conductor and a hole conductor; it further comprises a sensitising semiconductor, said sensitizing semiconductor being located at an interface between said electron conductor and said hole conductor. In particular, the sensitizing semiconductor is in form of quantum-dots. A solid state sensitized photovoltaic cell comprises such a heterojunction between two electrodes.

Abstract: An apparatus for manipulating fluid samples comprises a micro-chip device having first and second covered channels, each channel having openings at both ends. The channels intersect to form a common intersection. Three of the openings of the channels are connected to a multi-port valve to control pressure in the device.

Abstract: A method of generating an image incorporating a microstructure includes the steps of obtaining an original image, generating a microstructure, and rendering a region or the whole said original image with said microstructure. The operation of generating the microstructure includes an automatic synthesis of microstructure elements from original microstructure shapes.

Abstract: Moving components with dimensions much smaller than what micro-electro-mechanical system (MEMS) technology can accomplish in terms of force generated and power efficiency, are integrated onto micro-systems. These moving components referred to herein as “bio-components” are special bacteria (magnetotactic bacteria) where the motion of these bio-components can be controlled by generating an “artificial pole” by a magnetic field generated by a constant electrical current that can be varied to change the location of the “artificial pole” from an electrical system such as an embedded electronic micro-circuit. According to the present invention, it is possible through a software program or codes, to control the direction of motion of these magnetotactic bacteria, for example, by downloading such program onto the embedded electronics (controller or the like), and to generate the required magnetic field to control such bacteria to accomplish a particular task.

Abstract: The invention concerns an electroluminescent device comprising first and second substantially parallel mirrors for converting electron-hole pairs into photons, and means for generating electrons and holes. The converting means and the first and second mirrors are designed to ensure the confinement between the first and second mirrors of photons having at least a selected wavelength, associated with a guided propagation mode. Additionally, the device comprises light extracting means which communicate with part at least of the converting means and the generating means, comprised between the first and second mirrors, and are designed to extract therefrom part at least of the photons in guided mode, so that they reach outside.