Abstract: A process for consolidating a hydrogel including alginate and gelatin, which includes a step of consolidation by crosslinking of the hydrogel using a suitable solution, in order to give it particularly advantageous mechanical properties. Also, the use of this crosslinking solution for consolidating the structure of a hydrogel including alginate and gelatin, and to a hydrogel obtained by this process. Additionally, a process for consolidating the structure of a hydrogel including alginate and gelatin, this process including preparing the hydrogel, shaping it, then bringing it into contact with suitable consolidation agents. Further, the hydrogel obtained by this process. In all these aspects, the hydrogel can further include fibrinogen and/or living cells.
Type:
Application
Filed:
June 24, 2022
Publication date:
October 10, 2024
Applicants:
UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE SUP CHIMIE PHYS ELECTRONIQ LYON, LAB SKIN CREATIONS
Inventors:
Christophe MARQUETTE, Emma PETIOT, Laura CHASTAGNIER, Audrey CHERBLANC, Morgan DOS SANTOS, Amélie THEPOT, Baptiste GODET
Abstract: Three-dimensional body implants including a hydrogel, which includes cross-linked alginate and gelatin, and in particular breast implants. The hydrogel of the implants has a mechanical strength of 1 kPa to 1000 kPa, and the hydrogel of the implants may further include fibrinogen. The implants include a porous zone, and the implants are acellular, i.e., free of cells during their manufacture.
Type:
Application
Filed:
June 24, 2022
Publication date:
November 16, 2023
Applicants:
UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE CENTRALE DE NANTES, ECOLE SUP CHIMIE PHYS ELECTRONIQ LYON, HEALSHAPE
Inventors:
Christophe MARQUETTE, Audrey CHERBLANC, Morgan DOS SANTOS, Luciano VIDAL, Emma PETIOT, Laura CHASTAGNIER, Amélie THEPOT, Baptiste GODET