Abstract: The current invention provides an endotracheal tube fabricated with an array of electrodes disposed on an inflatable cuff on the tube. The array of electrodes includes multiple sense electrodes and a current electrode. The array of electrodes on the inflatable cuff is applied using a positive displacement dispensing system, such as a MicroPen®. A ground electrode is disposed on the tube approximately midway between the inflatable cuff and the midpoint of the endotracheal tube. The endotracheal tube is partially inserted into a mammalian subject's airway such that when the inflatable cuff is inflated, thereby fixing the tube in position, the array of electrodes is brought into close contact with the tracheal mucosa in relative proximity to the aorta. The endotracheal tube is useful in the measurement of cardiac parameters such as cardiac output.