Abstract: An aqueous solution containing a bacterially effective concentration of taurolidine and/or taurultam together with a parenterally acceptable polyol. The aqueous solution is particularly suitable for parenteral administration.
Abstract: A hydrogel sheet for use as a wound dressing with capillaries permitting wound exudate to pass through the sheet while not permitting bacteria to infect the wound is disclosed. The total cross-sectional area of the capillaries represents 0.5 to 3.0 percent of the area of the sheet. The sheets do not stick to the wound surface and allow large quantities of wound exudate to be removed from the wound.
November 1, 1989
Date of Patent:
December 31, 1991
Ed Geistlich Sohne A.G. fur Chemische Industrie
Abstract: Pharmaceutical depot preparation for implantation into base tissue comprising natural bone mineral from which the naturally associated fat and bone-proteins have been removed whereby said bone is sterile and non-allergenic, said bone mineral having absorbed thereon and/or adsorbed therein one or more physiologically active substances. The physiologically active substance is advantageously an antibiotic or taurolidine or tauraltam or a protein or polypeptide assisting bone regeneration.
Abstract: A composition comprising a resorbable aqueous gel having dissolved or dispersed therein one or more water-soluble medicaments is of use in the treatment of wounds.Such a composition is of use in a method of healing an infection in a cavity in bone or other tissue whereby the resorbable aqueous gel is placed in the cavity and allowed to remain there until resorbed, the aqueous phase of the gel containing the water soluble medicament.The medicament is preferably an antibiotic or a methylol transfer antibacterial.
Abstract: The invention provides compositions comprising oleum hyoscyami together with a pharmaceutical carrier or excipient and a method for the prevention or treatment of scar tissue whereby existing scar tissue or a wound or surgical incision is treated topically with oleum hyoscyami.
Abstract: The present invention provides a method of combatting endotoxaemia whereby there is administered to a patient an effective amount of a compound of the formula: ##STR1## where R.sup.1 is hydrogen or an alkyl group with 1-6 carbon atoms and R.sup.2 is hydrogen or an alkyl group with 1-6 carbon atoms or a group of formula: ##STR2## R.sup.1 is preferably hydrogen and R.sup.2 is preferably hydrogen or a group of formula II; the most preferred compound is bis-(1,1-dioxo-perhydro-1,2,4-thiadiazin-4-yl)-methane.
Abstract: This invention relates to novel preparations for the treatment and for prophylaxis of tooth and gum infections, and in particular parodontosis, comprising derivatives of thiadiazine as active ingredient. Pharmaceutical compositions according to the invention are described and exemplified.
Abstract: N-Sulphamoylphenyl-substituted imidazolidin-4-ones having useful anti-epileptic activity are prepared by cyclising N-sulphamoylphenyl-substituted .alpha.-aminoacetamides with formaldehyde or a reactive derivative of carbonic acid, or by reacting N-halosulphonylphenyl-substituted imidazolidin-4-ones with ammonia.