Patents Assigned to Edge Biosystems
  • SIMULTANEOUS CLONING OF GENES AND EXPRESSION OF RECOMBINANT PROTEINS IN ESCHERICHIA COLI
    Publication number: 20080020443
    Abstract: The mutation of the endA and recA genes in E. coli strain BL21 creates features that are very attractive for protein expression and cloning in a single prokaryotic system, including rapid cell growth, high transformation efficiency, rapid plasmid replication to high densities, and high plasmid stability. When specially prepared for competence, these strains are highly useful for both cloning and protein expression.
    Type: Application
    Filed: February 13, 2007
    Publication date: January 24, 2008
    Applicant: EDGE BIOSYSTEMS
    Inventors: Reyes Candau, Robert Donahue, John Seed
  • Filterplate
    Patent number: D623300
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: September 7, 2010
    Assignee: Edge Biosystems
    Inventors: Oscar Zimerman, Stephen G. Young