Abstract: The present invention relates to vaccines comprising a ShK domain of a filarial nematode protein. These vaccines may be used for the prevention and/or treatment of filarial nematode infections. The invention also relates to novel proteins comprising a ShK domain of a filarial nematode protein and pharmaceutical compositions. The invention may be used for the prevention and/or treatment of filarial nematode infections in canine subjects, and also in human subjects.
Type:
Grant
Filed:
May 8, 2018
Date of Patent:
February 16, 2021
Assignees:
The University of Liverpool, Edinburgh University
Inventors:
Ben Makepeace, David Taylor, Simon Babayan, Stuart Armstrong, Mark Blaxter
Abstract: The present invention relates to vaccines comprising a ShK domain of a filarial nematode protein. These vaccines may be used for the prevention and/or treatment of filarial nematode infections. The invention also relates to novel proteins comprising a ShK domain of a filarial nematode protein and pharmaceutical compositions. The invention may be used for the prevention and/or treatment of filarial nematode infections in canine subjects, and also in human subjects.
Type:
Grant
Filed:
February 11, 2015
Date of Patent:
June 12, 2018
Assignees:
THE UNIVERSITY OF LIVERPOOL, EDINBURGH UNIVERSITY
Inventors:
Ben Makepeace, David Taylor, Simon Babayon, Stuart Armstrong, Mark Blaxter