Patents Assigned to EDITAS MEDICINE, INC.
  • Systems and methods for one-shot guide RNA (ogRNA) targeting of endogenous and source DNA
    Patent number: 9963719
    Abstract: Engineered nucleic acids encoding genome editing system components are provided, as are engineered RNA-guided nucleases that include inserts encoded in part by cellular genomic or other sequences recognized by guide RNAs.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: May 8, 2018
    Assignee: EDITAS MEDICINE, INC.
    Inventors: Ari E. Friedland, Hariharan Jayaram, Barrett Ethan Steinberg
  • CRISPR/CAS-RELATED METHODS AND COMPOSITIONS FOR TREATING HIV INFECTION AND AIDS
    Publication number: 20180119123
    Abstract: CRISPR/CAS-related systems, compositions and methods for editing CCR5 and/or CXCR4 genes in human cells are described, as are cells and compositions including cells edited according to the same.
    Type: Application
    Filed: November 10, 2017
    Publication date: May 3, 2018
    Applicant: EDITAS MEDICINE, INC.
    Inventors: Jennifer Leah Gori, G. Grant Welstead, Penrose Odonnell
  • CRISPR/CAS-RELATED METHODS, COMPOSITIONS AND COMPONENTS
    Publication number: 20180112213
    Abstract: CRISPR/Cas-related compositions and methods which provide for efficient gene editing of eukaryotic cells using modified gRNAs.
    Type: Application
    Filed: March 25, 2016
    Publication date: April 26, 2018
    Applicants: Editas Medicine, Inc., Editas Medicine, Inc.
    Inventors: Gordon Grant Welstead, Jennifer Leah Gori, Jack Michael Heath, David A. Bumcrot
  • CRISPR/CAS-related methods and compositions for treating leber's congenital amaurosis 10 (LCA10)
    Patent number: 9938521
    Abstract: CRISPR/CAS-related compositions and methods for treatment of Leber's Congenital Amaurosis 10 (LCA10) are disclosed.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: April 10, 2018
    Assignee: EDITAS MEDICINE, INC.
    Inventors: Morgan L. Maeder, David A. Bumcrot, Shen Shen
  • CRISPR-related methods and compositions with governing gRNAS
    Patent number: 9834791
    Abstract: Disclosed herein are methods and compositions useful in targeting a payload to, or editing a target nucleic acid, where a governing gRNA molecule is used to target, optionally inactivate, a Cas9 molecule or a Cas9 molecule/gRNA complex.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: December 5, 2017
    Assignees: Editas Medicine, Inc., The Broad Institute Inc., Massachusetts Institute of Technology, University of Iowa Research Foundation
    Inventors: Feng Zhang, Deborah Palestrant, Beverly Davidson, Jordi Mata-Fink, Edgardo Rodriguez, Alexis Borisy
  • CRISPR/CAS-RELATED METHODS AND COMPOSITIONS FOR TREATING CYSTIC FIBROSIS
    Publication number: 20170022507
    Abstract: CRISPR/CAS-related compositions and methods for treatment of Cystic Fibrosis (CF).
    Type: Application
    Filed: October 7, 2016
    Publication date: January 26, 2017
    Applicant: EDITAS MEDICINE, INC.
    Inventors: Deepak Reyon, Morgan L. Maeder, Ari E. Friedland, Grant G. Welstead, David A. Bumcrot
  • CRISPR/CAS-RELATED METHODS AND COMPOSITIONS FOR TREATING HIV INFECTION AND AIDS
    Publication number: 20170007679
    Abstract: CRISPR/CAS-related compositions and methods for treatment of a subject at risk for or having a HIV infection or AIDS are disclosed.
    Type: Application
    Filed: September 23, 2016
    Publication date: January 12, 2017
    Applicant: EDITAS MEDICINE INC.
    Inventors: Morgan L. Maeder, Ari E. Friedland, G. Grant Welstead, David A. Bumcrot
  • CRISPR-RELATED METHODS AND COMPOSITIONS
    Publication number: 20160237455
    Abstract: Methods and compositions useful in targeting a payload to or editing a target nucleic acid utilizing CRISPR/Cas9 and guide RNA (gRNA) are disclosed herein
    Type: Application
    Filed: September 26, 2014
    Publication date: August 18, 2016
    Applicant: Editas Medicine, Inc.
    Inventors: Alexandra GLUCKSMANN, Deborah PALESTRANT, Louis Anthony TARTAGLIA, Jordi MATA-FINK, Agnieszka Dorota CZECHOWICZ
  • CRISPR-RELATED METHODS AND COMPOSITIONS WITH GOVERNING gRNAS
    Publication number: 20150232881
    Abstract: Disclosed herein are methods and compositions useful in targeting a payload to, or editing a target nucleic acid, where a governing gRNA molecule is used to target, optionally inactivate, a Cas9 molecule or a Cas9 molecule/gRNA complex.
    Type: Application
    Filed: November 7, 2014
    Publication date: August 20, 2015
    Applicant: EDITAS MEDICINE, INC.
    Inventors: Alexandra Glucksmann, Deborah Palestrant, Louis Anthony Tartaglia, Jordi Mata-Fink, Agnieszka Dorota Czechowicz, Alexis Borisy