Abstract: The present invention relates to methods for the diagnosis and treatment of melanoma. In particular, the invention relates to methods for the diagnosis and treatment of early stage melanoma by measuring the expression of one or more autoantibodies selected from the group consisting of anti-ZBTB7B, anti-PRKCH, anti-TP53, anti-PCTK1, anti-PQBP1, anti-UBE2V1, anti-IRF4, anti-MAPK8_tv2, anti-MSN and anti-TPM1. Further, the present invention relates to kits comprising one or more reagents and/or devices when used in performing the methods for the diagnosis and treatment of melanoma.

Abstract: A pest detector (1) for actively detecting pest activity within the environs of a structure. The pest detector includes a pest detection unit (2) that detects pest activity through the analysis of sounds of pest activity within a pest bait. The pest bait is typically timber or cellulose material (3). Upon detection of pest activity, a signal is sent to wireless transmitting device which transmits a radio frequency signal which includes data identifying the pest detector. Advantageously, the radio frequency is in the cellular radio frequency spectrum and is transmitted via the cellular radio network to a remote base station. The signal can be in the form of a short message service message. In this way, the pest detector can be remotely monitored and any pest activity dealt with appropriately. The pest detector can be used within a pest detection system and the pest detection unit can be retrofitted to known pest monitoring systems.

Abstract: A tracking apparatus (1) comprising: a first mobile transceiver unit (2), and a second mobile transceiver unit (3), the first mobile transceiver unit being in wireless communication with the second mobile transceiver unit for the transfer of data therebetween, the first mobile transceiver unit being arranged for location within an environment and being operable to determine data regarding the environment and to emit some or all of the determined data which is received by the second mobile transceiver unit for storage thereon when it is determined by the first mobile transceiver unit that the second mobile transceiver unit is located within a distance of the first mobile transceiver unit.

Abstract: A pest detector (1) for actively detecting pest activity within the environs of a structure. The pest detector includes a pest detection unit (2) that detects pest activity through the analysis of sounds of pest activity within a pest bait. The pest bait is typically timber or cellulose material (3). Upon detection of pest activity, a signal is sent to wireless transmitting device which transmits a radio frequency signal which includes data identifying the pest detector. Advantageously, the radio frequency is in the cellular radio frequency spectrum and is transmitted via the cellular radio network to a remote base station. The signal can be in the form of a short message service message. In this way, the pest detector can be remotely monitored and any pest activity dealt with appropriately. The pest detector can be used within a pest detection system and the pest detection unit can be retrofitted to known pest monitoring systems.

Abstract: The present invention provides methods for predicting whether a subject will develop a disease capable of affecting cognitive function. More specifically, the present invention relates to the predictive detection of neurological diseases in a subject. The methods and systems provided enable a quantitative assessment and theoretical predictions of neocortical amyloid loading or amyloid beta levels based on the measurement of biomarkers in biological fluids that will provide an indication of whether a subject is likely to develop a neurological disease, such as Alzheimer's disease (AD).

Abstract: The present invention provides an optical connection component which comprises a solid state laser component for emitting a modulated beam of light in response to an applied electrical signal. The optical connection component also comprises an optical lens positioned relative to the solid state laser component at a predetermined position in which the optical lens reduces divergence of the emitted beam of light. The optical lens is formed at the predetermined position in a manner such that the optical lens is immobile relative to the solid state laser component. The optical connection component further comprises an optical waveguide having a core for guiding the light. The optical waveguide has first and second end-portions. The first end-portion is positioned for coupling the modulated light from the optical lens into the core.

Abstract: A tracking apparatus (1) comprising: a first mobile transceiver unit (2), and a second mobile transceiver unit (3), the first mobile transceiver unit being in wireless communication with the second mobile transceiver unit for the transfer of data therebetween, the first mobile transceiver unit being arranged for location within an environment and being operable to determine data regarding the environment and to emit some or all of the determined data which is received by the second mobile transceiver unit for storage thereon when it is determined by the first mobile transceiver unit that the second mobile transceiver unit is located within a distance of the first mobile transceiver unit.

Abstract: The present disclosure provides an optical connection system which comprises optical components that include a plurality of vertical cavity surface emitting lasers (VCSELs) for emitting modulated light in response to applied electrical signals and a plurality of receivers for receiving the emitted light. The optical components are arranged in at least two monolithically integrated modules each comprising at least two of the optical components. The optical connection system further comprises at least one light guiding component for guiding the light between the VCSELs and the receivers. The optical connection system also comprises coupling elements for coupling the at least one light guiding component to the monolithically integrated modules such that in use light is transmitted between modules via the at least one light guiding component.

Abstract: Provided are a method of fabricating a microlens using selective etching of a compound semi-conductor and a method of fabricating a photoelectric device having the microlens. The formation of the microlens includes patterning a compound semiconductor layer and removing a lateral surface of the compound semiconductor layer to form a roughly hemispheric lens. The lateral surface of the compound semiconductor layer is removed by a digital alloy method. In particular, the lateral surface of the compound semiconductor layer is removed by a wet etching process.

Abstract: The present invention provides an optical connection component which comprises a solid state laser component for emitting a modulated beam of light in response to an applied electrical signal. The optical connection component also comprises an optical lens positioned relative to the solid state laser component at a predetermined position in which the optical lens reduces divergence of the emitted beam of light. The optical lens is formed at the predetermined position in a manner such that the optical lens is immobile relative to the solid state laser component. The optical connection component further comprises an optical waveguide having a core for guiding the light. The optical waveguide has first and second end-portions. The first end-portion is positioned for coupling the modulated light from the optical lens into the core.