Abstract: An infection detection device is configured to continuously monitor a temperature of a periwound of a user and includes a dock and a drive. The dock includes an adhesive layer having an adhesive coating on a wound side thereof, a first dock portion and a second dock portion. The drive is configured to be inserted into a cavity of the dock and includes a printed circuit board, a plurality of first temperature sensors and at least one second temperature sensor. The printed circuit board is positioned along a base of the drive, and has a first printed circuit board portion and a second printed circuit board portion. The plurality of first temperature sensors extend from the first printed circuit board portion and through the first dock portion. The at least one second temperature sensor extends from the second printed circuit board portion and through the second dock portion.