Abstract: An antimicrobial cover system for tubular structures includes a pair of identical cover portions. Each cover portion's outer surface is defined by an antimicrobial material and its inner surface is longitudinally corrugated. Each cover portion has a first longitudinal edge and a second longitudinal edge. The first longitudinal edge includes a first tab and a first socket, and the second longitudinal edge includes a second tab and a second socket. When the cover portions are adapted to encase a tubular structure, the first tab of a first of the cover portions is engaged in the second socket of a second of the cover portions, and the second tab of the second of the cover portions is engaged in the first socket of the first of the cover portions.