Abstract: This disclosure provides microRNA (miRNA)-based tests and treatment protocols for identifying and/or treating pregnant human beings at risk for a placental bed disorder during pregnancy, as well as reagents and/or kits relating to the same.
Type:
Application
Filed:
March 6, 2020
Publication date:
June 9, 2022
Applicant:
EDWARD E. WINGER, M.D., PROFESSIONAL CORPORATION
Abstract: The invention is directed to methods and compositions for collecting a non-placental biological samples of cells and quantifying and comparing levels of expression of microRNAs to characterize a preeclampsia-related condition. The samples may be collected before or after an intervention or may be collected over a period of time. One of the samples may be a control sample. Patients may then be treated according to their response.
Type:
Application
Filed:
February 13, 2019
Publication date:
August 15, 2019
Applicant:
Edward E. Winger, M.D., Professional Corporation
Abstract: The invention is directed to methods and compositions for collecting a non-placental biological samples of cells and quantifying and comparing levels of expression of microRNAs to characterize a preeclampsia-related condition. The samples may be collected before or after an intervention or may be collected over a period of time. One of the samples may be a control sample. Patients may then be treated according to their response.
Type:
Grant
Filed:
May 21, 2013
Date of Patent:
June 18, 2019
Assignee:
Edward E. Winger, M.D., Professional Corporation
Abstract: A method for performing real time, homogeneous assay of a target nucleic acid comprising annealing a labeled, ribo-oligonucleotide probe to the target DNA sequence and degrading a portion of the probe with RNase H to release labeled fragments. Sequential measurements of the released fragments permits kinetic characterization of the presence of the target sequence. Preferably, the assay is integrated into a polymerase chain reaction so that target amplification can be detected in real time.
Type:
Grant
Filed:
July 26, 1996
Date of Patent:
December 29, 1998
Assignee:
Edward E. Winger
Inventors:
Edward E. Winger, Donald J. Kessler, David E. Hargrove