Patents Assigned to Edward Mendell Co., Inc.
  • Patent number: 5399358
    Abstract: A sustained release oral solid dosage form of metoprolol pharmaceutical formulation includes a sustained release excipient including a gelling agent, an inert pharmaceutical diluent, a cationic cross-linking agent, and metoprolol provides release of metoprolol for at least about 24 hours. In certain embodiments, the sustained release formulation further includes a hydrophobic material.
    Type: Grant
    Filed: November 12, 1993
    Date of Patent: March 21, 1995
    Assignee: Edward Mendell Co., Inc.
    Inventors: Anand R. Baichwal, John N. Staniforth
  • Patent number: 5330761
    Abstract: The present invention relates to a controlled release bioadhesive tablet which includes a locally active agent, a heterodisperse gum matrix, and a pharmaceutically acceptable diluent. In certain preferred embodiments, the tablet further includes an additional bioadhesive agent. The final product adheres to mucous membranes and releases the locally active agent over a desired period of time. Also disclosed is a bioadhesive excipient useful in the preparation of these tablets.
    Type: Grant
    Filed: January 29, 1993
    Date of Patent: July 19, 1994
    Assignee: Edward Mendell Co. Inc.
    Inventor: Anand R. Baichwal
  • Patent number: 5169639
    Abstract: Controlled release verapamil tablets are disclosed. The tablets include an excipient having a hydrophilic material, preferably containing a mixture of xanthan gum/locust bean gum, and an inert diluent.
    Type: Grant
    Filed: July 25, 1991
    Date of Patent: December 8, 1992
    Assignee: Edward Mendell Co., Inc.
    Inventors: Anand R. Baichwal, John N. Staniforth
  • Patent number: 5135757
    Abstract: A free-flowing directly compressible granulation useful as a slow release pharmaceutical excipient is disclosed. The excipient includes a hydrodrophilic matrix which includes heteropolysaccharide and a polysaccharide material capable of cross-linking the heteropolysaccharide, and an inert diluent.
    Type: Grant
    Filed: January 16, 1991
    Date of Patent: August 4, 1992
    Assignee: Edward Mendell Co., Inc.
    Inventors: Anand R. Baichwal, John N. Staniforth
  • Patent number: 5128143
    Abstract: A slow release pharmaceutical excipient of an inert diluent and a hydrodrophilic material including xanthan gum and a galactomannan gum capable of cross-linking the xanthan gum in the presence of aqueous solutions.
    Type: Grant
    Filed: March 9, 1990
    Date of Patent: July 7, 1992
    Assignee: Edward Mendell Co., Inc.
    Inventors: Anand R. Baichwal, John N. Staniforth
  • Patent number: 4994276
    Abstract: A free-flowing directly compressible granulation useful as a slow release pharmaceutical excipient is disclosed. The excipient includes a hydrodrophilic matrix which includes a heteropolysaccharide and a polysaccharide material capable of cross-linking the heteropolysaccharide, and an inert diluent.
    Type: Grant
    Filed: September 19, 1988
    Date of Patent: February 19, 1991
    Assignee: Edward Mendell Co., Inc.
    Inventors: Anand R. Baichwal, John N. Staniforth