Abstract: An endometrial sampler has an outer catheter and an inner plunger slidable within the catheter. The catheter has a coaxial opening at its tip and two side openings located diametrically opposite one another close to the tip, the side openings being elongate along the axis of the catheter. The tip of the plunger projects into the tip opening to form a smooth surface to the sampler. An O-ring seal on the plunger is located rearwardly of the side openings so that suction is applied to both the side openings and the tip opening when the plunger is pulled rearwardly.