Patents Assigned to Efamol Ltd.
  • Patent number: 5246726
    Abstract: Pharmaceutically acceptable compositions of one or more n-6 or n-3 essential fatty acids, particularly gamma-linolenic acid, dihomo-gamma-linolenic acid, or eicosapentaenoic acid, and assimilable iron compounds, in dosage unit form optionally with a diluent or carrier, said acids being present as such or as derivatives convertible in the body thereto and the amounts of said acids or derivatives being 1 mg to 100 g (calculated as gamma-linolenic acid) and of said iron compounds 0.1 mg to 10 g (calculated as iron) or submultiples of said amounts convenient for daily administration thereof.
    Type: Grant
    Filed: April 21, 1992
    Date of Patent: September 21, 1993
    Assignee: Efamol Ltd.
    Inventors: David F. Horrobin, Michel E. Begin
  • Patent number: 4937262
    Abstract: Derivatives of platinum group metals, particularly platinum itself, wherein the metal is linked to one or more pharmaceutically acceptable steroid, fatty acid or other lipophilic residues aiding transport of the metal across cell membranes in the body, particularly fatty acid amine or fatty acid amide groups ##STR1## where R is a hydrocarbon group, suitably of 10 to 30 carbon atoms. The derivatives are useful in the treatment of cancer.
    Type: Grant
    Filed: August 24, 1987
    Date of Patent: June 26, 1990
    Assignee: EFAMOL Ltd.
    Inventor: Bruce C. Davidson
  • Patent number: 4888326
    Abstract: A pharmaceutical composition comprises one or more essential fatty acids, for example, .gamma.-linolenic acid or dihomo-.gamma.-linolenic acid, in conjunction with rutin, troxerutin or other bioflavonoid. The composition is useful in the treatment of inflammation or defective T-lymphocyte function.
    Type: Grant
    Filed: March 4, 1988
    Date of Patent: December 19, 1989
    Assignee: Efamol Ltd.
    Inventor: David F. Horrobin
  • Patent number: 4868212
    Abstract: A method of treatment of atopic disorders, including eczema, asthma, allergies (especially allergic rhinitis), migraine and disorders associated with atopy including Crohn's disease, ulcerative colitis, otitis media, nephrotic syndrome, or benign breast disease, or breast or other cancer, or diabetes, or alcoholism, with effective amounts of one or more of the metabolites of linoleic acid (GLA, DGLA, AA, 22:4n-6 or 22:5n-6) and one or more of the metabolites of .alpha.-linolenic acid (18:4n-3, 20:4n-3, 20:5n-3, 22:5n-3 or 22:6n-3) are administered as such or in the form of an ester, salt, amide or other derivative convertible in the body thereto alone or in an acceptable pharmaceutical carrier or diluent.
    Type: Grant
    Filed: February 9, 1989
    Date of Patent: September 19, 1989
    Assignee: Efamol Ltd.
    Inventor: David F. Horrobin
  • Patent number: 4837221
    Abstract: This invention provides for therapy of tumours susceptible to necrosis by a porphyrin when an appropriate porphyrin compound is administered to locate in the tumor followed by illumination with light of a wavelength absorbed by the compound, making use of meso-porphyrins of the formula: ##STR1## where n=1 to 3 and each substitutent R, the same or different and at the same or different position in its respective substituent phenyl ring or other aromatic group replacing that ring, is an hydroxy, amino or sulphydryl group, by association of said meso-porphyrins with a suitable pharmaceutical diluent or carrier.
    Type: Grant
    Filed: March 26, 1987
    Date of Patent: June 6, 1989
    Assignee: Efamol Ltd.
    Inventors: Raymond Bonnett, Morris C. Berenbaum
  • Patent number: 4806569
    Abstract: A method of treatment of atopic disorders, including eczema, asthma, allergies (especially allergic rhinitis), migraine and disorders associated with atopy including Crohn's disease, ulcerative colitis, otitis media, nephrotic syndrome, or benign breast disease, or breast or other cancer, or diabetes, or alcoholism, with effective amounts of one or more of the metabolites of linoleic acid (GLA, DGLA, AA, 22:4n-6 or 22:5n-6) and one or more of the metabolites of .alpha.-linolenic acid (18:4n-3), 20:4n-3, 20:5n-3, 22:5n-3 or 22:6n-3) are administered as such or in the form of an ester, salt, amide or other derivative convertible in the body thereto along or in an acceptable pharmaceutical carrier or diluent.
    Type: Grant
    Filed: May 4, 1987
    Date of Patent: February 21, 1989
    Assignee: Efamol, Ltd.
    Inventor: David F. Horrobin
  • Patent number: 4738853
    Abstract: A method of maintaining hens or other domesticated birds for egg production, comprises giving the birds feed supplemented with .gamma.-linolenic acid or one or more higher acids in the n-6 series, in the form of the free acid or as an ester, amide, phospholipid, salt or other physiologically acceptable derivative convertible in the bird's body to, or having the effect of, the free acid.
    Type: Grant
    Filed: April 4, 1985
    Date of Patent: April 19, 1988
    Assignee: Efamol Ltd.
    Inventor: David F. Horrobin