Patents Assigned to Egis Pharmaceutical
  • Patent number: 11154535
    Abstract: Disclosed are gel compositions suitable for the topical administration of an active compound having poor solubility and skin penetration, for example, of a COX-2 inhibitor compounds, processes of preparation thereof and methods of use thereof for the treatment of indications treatable by the active compound.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: October 26, 2021
    Assignee: EGIS Pharmaceuticals PLC
    Inventors: Endre Mikulásik, Tamás Spaits, Ágota Szakálynè Sinka
  • Patent number: 10045965
    Abstract: Disclosed are gel compositions suitable for the topical administration of an active compound having poor solubility and skin penetration, for example, of a COX-2 inhibitor compounds, processes of preparation thereof and methods of use thereof for the treatment of indications treatable by the active compound.
    Type: Grant
    Filed: April 9, 2015
    Date of Patent: August 14, 2018
    Assignee: EGIS Pharmaceuticals PLC
    Inventors: Endre Mikulásik, Tamás Spaits, Ágota Szakályné Sinka
  • Patent number: 10045935
    Abstract: Disclosed are gel compositions suitable for the topical administration of an active compound having poor solubility and skin penetration, for example, of a COX-2 inhibitor compounds, processes of preparation thereof and methods of use thereof for the treatment of indications treatable by the active compound.
    Type: Grant
    Filed: July 31, 2012
    Date of Patent: August 14, 2018
    Assignee: EGIS PHARMACEUTICALS PLC
    Inventors: Endre Mikulásik, Tamás Spaits, Ágota Szakályné Sinka
  • Publication number: 20140161889
    Abstract: Disclosed are gel compositions suitable for the topical administration of an active compound having poor solubility and skin penetration, for example, of a COX-2 inhibitor compounds, processes of preparation thereof and methods of use thereof for the treatment of indications treatable by the active compound.
    Type: Application
    Filed: February 13, 2014
    Publication date: June 12, 2014
    Applicant: EGIS PHARMACEUTICALS PLC
    Inventors: Endre Mikulásik, Tamás Spaits, Ágota Szakálynè Sinka
  • Publication number: 20140079791
    Abstract: The subject of the present invention is a transdermal preparation containing pharmaceutically active ingredient, wherein the particles of the active ingredient are coated with highly volatile silicones or a mixture thereof, and these coated particles are dispersed in a gel or cream base. The volatile silicone component is hexamethyldisiloxane and/or octamethyltrisiloxane and/or decamethylpentacyclo-siloxane. A further subject of the present invention is a method for the preparation of such pharmaceutical compositions.
    Type: Application
    Filed: November 15, 2013
    Publication date: March 20, 2014
    Applicant: EGIS Pharmaceuticals Public Limited Company
    Inventors: Endre Mikulásik, Patrik Fazekas
  • Publication number: 20140037738
    Abstract: Disclosed are gel compositions suitable for the topical administration of an active compound having poor solubility and skin penetration, for example, of a COX-2 inhibitor compounds, processes of preparation thereof and methods of use thereof for the treatment of indications treatable by the active compound.
    Type: Application
    Filed: July 31, 2012
    Publication date: February 6, 2014
    Applicant: EGIS PHARMACEUTICALS PLC
    Inventors: Endre MIKULÁSIK, Tamás SPAITS, Ágota SZAKÁLYNÉ SINKA
  • Publication number: 20140039028
    Abstract: Disclosed are gel compositions suitable for the topical administration of an active compound having poor solubility and skin penetration, for example, of a COX-2 inhibitor compounds, processes of preparation thereof and methods of use thereof for the treatment of indications treatable by the active compound.
    Type: Application
    Filed: September 13, 2013
    Publication date: February 6, 2014
    Applicant: EGIS Pharmaceuticals PLC
    Inventors: Endre Mikulásik, Tamás Spaits, Ágota Szakálynè Sinka
  • Patent number: 8603537
    Abstract: Prasugrel containing quickly released stable oral pharmaceutical compositions containing micronized prasugrel base, and starch or a starch derivative, and processes for the preparation thereof, and the use thereof for treating atherothrombotic events of patients suffering from acute coronary syndrome in which patients were subjected to percutaneous coronary intervention.
    Type: Grant
    Filed: April 2, 2012
    Date of Patent: December 10, 2013
    Assignee: Egis Pharmaceuticals PLC
    Inventors: András Fehér, Zsolt Zsigmong, Péter Tonka-Nagy, György Tibor Ujfalussy
  • Publication number: 20130259904
    Abstract: Prasugrel containing quickly released stable oral pharmaceutical compositions containing micronized prasugrel base, and starch or a starch derivative, and processes for the preparation thereof, and the use thereof for treating atherothrombotic events of patients suffering from acute coronary syndrome in which patients were subjected to percutaneous coronary intervention.
    Type: Application
    Filed: April 2, 2012
    Publication date: October 3, 2013
    Applicant: EGIS PHARMACEUTICALS PLC
    Inventors: András FEHÉR, Zsolt Zsigmond, Péter Tonka-Nagy, György Tibor Ujfalussy
  • Patent number: 5597822
    Abstract: The invention refers to pharmaceutical compositions for the prevention and/or treatment of gastrointestinal diseases connected with infections caused by Helicobacter pylori and a method for the treatment of such diseases.The pharmaceutical composition of the invention comprises as active ingredient a cyclic ketone derivative of the formula I ##STR1## wherein and R.sup.1 mean independently hydrogen or halo;R.sup.0 stands for hydrogen or a C.sub.1-4 alkoxy group;R.sup.2 and R.sup.3 independently represent hydrogen; a straight or branched chain C.sub.1-8 alkyl optionally substituted by a dimethylamino group; a C.sub.2-6 alkenyl or a C.sub.3-7 cycloalkyl group; orR.sup.2 and R.sup.3 together with the adjacent nitrogen atom form a 6-membered heterocyclic group containing an additional nitrogen atom that may bear a phenyl group optionally substituted by a C.sub.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: January 28, 1997
    Assignee: Egis Pharmaceutical
    Inventors: Eniko Szirt nee Kislelly, Zoltan Budai, Tibor Mezei, Gabor Blasko, Klara Kazo nee Daroczi, Andras Egyed, Gabor Gigler, Marton Fekete, Klara Reiter nee Esses, Gyula Simig, Katalin Szemeredi