Abstract: The invention refers to pharmaceutical compositions for the prevention and/or treatment of gastrointestinal diseases connected with infections caused by Helicobacter pylori and a method for the treatment of such diseases.The pharmaceutical composition of the invention comprises as active ingredient a cyclic ketone derivative of the formula I ##STR1## wherein and R.sup.1 mean independently hydrogen or halo;R.sup.0 stands for hydrogen or a C.sub.1-4 alkoxy group;R.sup.2 and R.sup.3 independently represent hydrogen; a straight or branched chain C.sub.1-8 alkyl optionally substituted by a dimethylamino group; a C.sub.2-6 alkenyl or a C.sub.3-7 cycloalkyl group; orR.sup.2 and R.sup.3 together with the adjacent nitrogen atom form a 6-membered heterocyclic group containing an additional nitrogen atom that may bear a phenyl group optionally substituted by a C.sub.
Type:
Grant
Filed:
May 18, 1995
Date of Patent:
January 28, 1997
Assignee:
Egis Pharmaceutical
Inventors:
Eniko Szirt nee Kislelly, Zoltan Budai, Tibor Mezei, Gabor Blasko, Klara Kazo nee Daroczi, Andras Egyed, Gabor Gigler, Marton Fekete, Klara Reiter nee Esses, Gyula Simig, Katalin Szemeredi