Abstract: The present disclosure provides compounds for the inhibition of soluble epoxide hydrolase and associate disease conditions, as well as a method of treating or preventing disorders in a subject by inhibition of soluble epoxide hydrolase.
Type:
Grant
Filed:
July 3, 2019
Date of Patent:
May 21, 2024
Assignee:
EicOsis, LLC
Inventors:
Bruce D. Hammock, Sung Hee Hwang, Karen M. Wagner, Cynthia B. McReynolds
Abstract: The invention discloses a new series of inhibitors of soluble epoxide hydrolase (sEH) with improved physical properties that enhance their druglikeness to treat sEH associated diseases such as chronic diabetic neuropathic pain.
Type:
Grant
Filed:
March 27, 2015
Date of Patent:
August 13, 2019
Assignee:
Eicosis, LLC
Inventors:
Bruce D. Hammock, Kin Sing Stephen Lee, Ahmet Bora Inceoglu