Patents Assigned to Ekos Corporation
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Patent number: 7914509Abstract: The invention relates to a catheter system. The system comprises a catheter body having a chamber containing a low acoustic impedance medium. The catheter body includes an elongated body with an external surface and an ultrasound transducer having an external side between a first end and a second end. The ultrasound transducer is positioned over the external surface of the elongated body such that the first end is adjacent to the chamber.Type: GrantFiled: February 15, 2007Date of Patent: March 29, 2011Assignee: Ekos CorporationInventors: Frederick J. Bennett, John Zhang, Gary Lichttenegger, James E. Rodriguey, Katsuro Tachibana
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Publication number: 20110060253Abstract: A catheter system for delivering ultrasonic energy to a treatment site within a body lumen comprises a tubular body. The tubular body has a proximal end, a distal end and an energy delivery section positioned between the proximal end and the distal end. The catheter further comprises an inner core configured for insertion into the tubular body. The inner core comprises a first ultrasound radiating member axially separated from a second ultrasound radiating member by an intermediate flexible joint region. The inner core further comprises an electrically conductive portion configured to allow a voltage difference to be applied to at least one of the ultrasound radiating members. The inner core further comprises a high impedance cap positioned proximal to at least one of the ultrasound radiating members.Type: ApplicationFiled: July 6, 2010Publication date: March 10, 2011Applicant: EKOS CORPORATIONInventor: RICHARD R. WILSON
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Publication number: 20110004105Abstract: An ultrasound catheter system and a method for operating an ultrasonic catheter at a treatment site within a patient's vasculature or tissue are disclosed. The ultrasound catheter system comprises a catheter having at least one ultrasonic element and a control system configured to generate power parameters that drive the at least one ultrasonic element to generate ultrasonic energy. The control system is configured to vary at least one of the power parameters and at least one physiological parameter by ramping the power parameter and the physiological parameter between two set of minimum and maximum values.Type: ApplicationFiled: July 2, 2010Publication date: January 6, 2011Applicant: EKOS CORPORATIONInventors: Azita Soltani, Kim R. Volz
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Publication number: 20100331763Abstract: An ultrasound catheter comprises an elongate tubular body is disclosed. The elongate tubular body has a proximal region and a distal region opposite the proximal region. The tubular body defines a central lumen having a central lumen surface that is electrically conductive. The ultrasound catheter further comprises an elongate, hollow inner core extending through the central lumen and has an inner core outer surface that is electrically conductive. The ultrasound catheter further comprises an ultrasound radiating member positioned within the distal region of the tubular body and between the tubular body and the inner core, such that the tubular body conductive surface and the inner core conductive surface are both in electrical contact with the ultrasound radiating member. The ultrasound catheter further comprises an insulating sleeve positioned between the tubular body and the inner core in a region proximal to the ultrasound radiating member.Type: ApplicationFiled: July 29, 2010Publication date: December 30, 2010Applicant: EKOS CORPORATIONInventors: RICHARD R. WILSON, TIM ABRAHAMSON, LEONARD R. OLIVER
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Patent number: 7828762Abstract: A catheter for delivering ultrasonic energy and therapeutic compounds to a treatment site within a patient's vasculature comprises a tubular body. The tubular body has a proximal region and a distal region opposite the proximal region. The catheter further comprises a plurality of fluid delivery lumens formed into the tubular body. The catheter further comprises an inner core configured for insertion into the tubular body. The inner core comprises an elongate electrical conductor having a plurality of flattened regions, each flattened region having a first flat side and a second flat side opposite the first flat side. The inner core further comprises a plurality of ultrasound radiating members mounted in pairs to the flattened regions of the elongate electrical conductor. A first ultrasound radiating member is mounted to the first flat side of the elongate electrical conductor, and a second ultrasound radiating member is mounted to the second flat side of the elongate electrical conductor.Type: GrantFiled: December 21, 2006Date of Patent: November 9, 2010Assignee: Ekos CorporationInventors: Richard R. Wilson, Robert L. Wilcox, Curtis Genstler, Tim Abrahamson, Wm. Gerrit Barrere, Amy Cohen, George Keilman, Leonard R. Oliver, Natalya Peskin
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Patent number: 7818854Abstract: A method comprises providing a substantially planar slab of piezoelectric material having a top surface. The method further comprises drilling a plurality of holes through the top surface and into the slab. The method further comprises making a plurality of cuts through the top surface and into the slab. The cuts form a plurality of polygons that are generally centered about one of the holes. The method further comprises plating the slab with an electrically conductive material. The method further comprises removing the electrically conductive material from the top surface of the slab. The method further comprises cutting the slab substantially parallel to the top surface.Type: GrantFiled: February 13, 2009Date of Patent: October 26, 2010Assignee: Ekos CorporationInventor: Richard R. Wilson
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Patent number: 7774933Abstract: An ultrasonic catheter is manufactured by providing an inner tube having an inner diameter sufficient to accommodate a guidewire, and mounting a tubular ultrasound radiating member around a distal region of the inner tube. Two electrical conductors are positioned along the inner tube, such that one of the electrical conductors contacts an inner side of the ultrasound radiating member while the other electrical conductor contacts an outer side of the ultrasound radiating member. An outer tube is then concentrically translated over the inner tube and the ultrasound radiating member, and radially shrunken onto the inner tube.Type: GrantFiled: May 4, 2006Date of Patent: August 17, 2010Assignee: Ekos CorporationInventors: Richard R. Wilson, Tim Abrahamson, Leonard R. Oliver
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Publication number: 20100204642Abstract: A method of delivery ultrasonic energy and a therapeutic compound to a treatment site and an ultrasonic catheter system are disclosed. The method comprises providing a catheter with a plurality of ultrasound radiating members, wherein the plurality of ultrasound radiating members are allocated into electrical groups comprising more than one ultrasound radiating member. The method further comprises independently driving each group of ultrasonic radiating members, and delivering the therapeutic compound through the catheter to the treatment site.Type: ApplicationFiled: April 16, 2010Publication date: August 12, 2010Applicant: EKOS CORPORATIONInventors: RICHARD R. WILSON, ROBERT L. WILCOX, CURTIS GENSTLER, TIM ABRAHAMSON, WM. GERRIT BARRERE, AMY COHEN, GEORGE KEILMAN, LEONARD R. OLIVER, NATALYA PESKIN
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Patent number: 7771372Abstract: A catheter system for delivering ultrasonic energy to a treatment site within a body lumen comprises a tubular body. The tubular body has a proximal end, a distal end and an energy delivery section positioned between the proximal end and the distal end. The catheter further comprises an inner core configured for insertion into the tubular body. The inner core comprises a first ultrasound radiating member axially separated from a second ultrasound radiating member by an intermediate flexible joint region. The inner core further comprises an electrically conductive portion configured to allow a voltage difference to be applied to at least one of the ultrasound radiating members. The inner core further comprises a high impedance cap positioned proximal to at least one of the ultrasound radiating members.Type: GrantFiled: January 5, 2004Date of Patent: August 10, 2010Assignee: Ekos CorporationInventor: Richard R. Wilson
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Patent number: 7727178Abstract: A catheter for delivering ultrasonic energy and therapeutic compounds to a treatment site within a patient's vasculature comprises a tubular body. The tubular body has a proximal region and a distal region opposite the proximal region. The catheter further comprises a plurality of fluid delivery lumens formed into the tubular body. The catheter further comprises an inner core configured for insertion into the tubular body. The inner core comprises an elongate electrical conductor having a plurality of flattened regions, each flattened region having a first flat side and a second flat side opposite the first flat side. The inner core further comprises a plurality of ultrasound radiating members mounted in pairs to the flattened regions of the elongate electrical conductor. A first ultrasound radiating member is mounted to the first flat side of the elongate electrical conductor, and a second ultrasound radiating member is mounted to the second flat side of the elongate electrical conductor.Type: GrantFiled: December 21, 2006Date of Patent: June 1, 2010Assignee: Ekos CorporationInventors: Richard R. Wilson, Robert L. Wilcox, Curtis Genstler, Tim Abrahamson, Wm. Gerrit Barrere, Amy Cohen, George Keilman, Leonard R. Oliver, Natalya Peskin
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Publication number: 20100081934Abstract: In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase. The method further comprises pausing the delivery of the microbubble therapeutic compound and delivering ultrasonic energy from the ultrasound catheter to the vascular occlusion during a second treatment phase while the delivery of microbubble therapeutic compound remains paused.Type: ApplicationFiled: December 2, 2009Publication date: April 1, 2010Applicant: EKOS CORPORATIONInventors: Azita Soltani, Douglas R. Hansmann
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Publication number: 20100063413Abstract: A method for monitoring clot dissolution in a patient's vasculature is disclosed. After a catheter is positioned at a treatment site in the patient's vasculature, a clot dissolution treatment procedure can be performed at the treatment site. The thermal parameter is measured at the treatment site. The clot dissolution treatment is then modified in response to the measured thermal parameter.Type: ApplicationFiled: August 25, 2009Publication date: March 11, 2010Applicant: EKOS CORPORATIONInventor: Kim Volz
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Publication number: 20100063414Abstract: A method for monitoring clot dissolution in a patient's vasculature is disclosed. After a catheter is positioned at a treatment site in the patient's vasculature, a clot dissolution treatment procedure can be performed at the treatment site. The thermal parameter is measured at the treatment site. The measured thermal parameter and/or the changes in the measured thermal parameter is then displayed.Type: ApplicationFiled: September 1, 2009Publication date: March 11, 2010Applicant: EKOS CORPORATIONInventor: Kim Volz
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Patent number: 7648478Abstract: In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase. The method further comprises pausing the delivery of the microbubble therapeutic compound and delivering ultrasonic energy from the ultrasound catheter to the vascular occlusion during a second treatment phase while the delivery of microbubble therapeutic compound remains paused.Type: GrantFiled: March 11, 2008Date of Patent: January 19, 2010Assignee: Ekos CorporationInventors: Azita Soltani, Douglas R. Hansmann
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Publication number: 20090144955Abstract: A method comprises providing a substantially planar slab of piezoelectric material having a top surface. The method further comprises drilling a plurality of holes through the top surface and into the slab. The method further comprises making a plurality of cuts through the top surface and into the slab. The cuts form a plurality of polygons that are generally centered about one of the holes. The method further comprises plating the slab with an electrically conductive material. The method further comprises removing the electrically conductive material from the top surface of the slab. The method further comprises cutting the slab substantially parallel to the top surface.Type: ApplicationFiled: February 13, 2009Publication date: June 11, 2009Applicant: Ekos CorporationInventor: Richard R. Wilson
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Patent number: 7509715Abstract: A method comprises providing a substantially planar slab of piezoelectric material having a top surface. The method further comprises drilling a plurality of holes through the top surface and into the slab. The method further comprises making a plurality of cuts through the top surface and into the slab. The cuts form a plurality of polygons that are generally centered about one of the holes. The method further comprises plating the slab with an electrically conductive material. The method further comprises removing the electrically conductive material from the top surface of the slab. The method further comprises cutting the slab substantially parallel to the top surface.Type: GrantFiled: June 2, 2005Date of Patent: March 31, 2009Assignee: Ekos CorporationInventor: Richard R. Wilson
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Publication number: 20080319376Abstract: An ultrasound catheter with fluid delivery lumens, fluid evacuation lumens and a light source is used for the treatment of intracerebral hemorrhages. After the catheter is inserted into a blood clot in the brain, a lytic drug can be delivered to the blood clot via the fluid delivery lumens while applying ultrasonic energy to the treatment site. As the blood clot is dissolved, the liquefied blood clot can be removed by evacuation through the fluid evacuation lumens.Type: ApplicationFiled: June 20, 2008Publication date: December 25, 2008Applicant: Ekos CorporationInventors: Robert L. Wilcox, Ronald L. Haas
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Publication number: 20080208109Abstract: In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase. The method further comprises pausing the delivery of the microbubble therapeutic compound and delivering ultrasonic energy from the ultrasound catheter to the vascular occlusion during a second treatment phase while the delivery of microbubble therapeutic compound remains paused.Type: ApplicationFiled: March 11, 2008Publication date: August 28, 2008Applicant: Ekos CorporationInventors: Azita Soltani, Douglas R. Hansmann
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Patent number: 7413556Abstract: A system for delivering ultrasound energy to a treatment section in a vessel is disclosed. The system includes a sheath with a utility lumen and an energy delivery section at least partially constructed from a material which transmits ultrasound energy. The system also includes a drug delivery member having a plurality of drug delivery ports which are positioned adjacent the energy delivery section. The system further includes an elongated body including at least one ultrasound element and configured to be movably positioned within the utility lumen to transmit the ultrasound energy from the ultrasound element through the energy delivery section.Type: GrantFiled: February 18, 2003Date of Patent: August 19, 2008Assignee: Ekos CorporationInventors: John Zhang, Gary Lichttenegger, James E. Rodriguey, Katsuro Tachibana
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Publication number: 20080171965Abstract: In one embodiment of the present invention, a method of applying ultrasonic energy to a treatment site within a patient's vasculature comprises positioning an ultrasound radiating member at a treatment site within a patient's vasculature. The method further comprises activating the ultrasound radiating member to produce pulses of ultrasonic energy at a cycle period T?1 second. The acoustic parameters such as peak power, pulse width, pulse repetition frequency and frequency or any combination of them can be varied non-linearly.Type: ApplicationFiled: January 8, 2008Publication date: July 17, 2008Applicant: EKOS CORPORATIONInventors: Azita Soltani, Kim R. Volz