Abstract: Methods are disclosed for modifying at least a portion of a porous polymeric surface. Such methods include contacting the porous polymeric surface with at least one polyelectrolyte, resulting in the physical adsorption of at least one polyelectrolyte onto the porous polymeric surface to form a charge modified surface. Such coated surfaces may be part of a device or apparatus, including electroosmotic pumps.
Type:
Grant
Filed:
January 30, 2007
Date of Patent:
January 11, 2011
Assignee:
Eksigent Technologies, Inc.
Inventors:
Darcee Deschamp Nelson, Klaus Joachim Dahl
Abstract: A liquid sample is prepared at a preparation site and then processed, e.g. in an HPLC column. The sample is prepared and conveyed to the device at a flow rate which is substantially less than the flow rate through the device. The different flow rates are preferably provided by variable rate working fluid supplies which drive the sample from the preparation site and through the device.
Type:
Application
Filed:
November 24, 2009
Publication date:
April 8, 2010
Applicant:
EKSIGENT TECHNOLOGIES, INC.
Inventors:
David W. Neyer, David J. Rakestraw, Jason E. Rehm
Abstract: Microfluidic systems including a principal microfluidic conduit (24), an adjacent dead volume (1) and a drain conduit (70) which mitigates the adverse effects of the dead volume on the operation of the system.
Abstract: Methods are disclosed for modifying at least a portion of a porous polymeric surface. Such methods include contacting the porous polymeric surface with at least one polyelectrolyte, resulting in the physical adsorption of at least one polyelectrolyte onto the porous polymeric surface to form a charge modified surface. Such coated surfaces may be part of a device or apparatus, including electroosmotic pumps.
Type:
Application
Filed:
January 30, 2007
Publication date:
July 31, 2008
Applicant:
Eksigent Technologies, Inc.
Inventors:
Darcee Deschamp Nelson, Klaus Joachim Dahl
Abstract: Methods and apparatus for mixing fluids are provided. The devices and methods operate without moving parts, and generate well-mixed fluids over a broad dynamic range of flow rates. Preferred embodiments include junction-type mixers, bundled mixers, and co-axial mixers. The devices and methods are optimized to produce rapid, accurate gradients to improve associated system throughput and reproducibility.
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