Abstract: The present invention relates to the formation of multi-domain specific binding molecules comprising VNARs. Specific binding domains that bind to Tumour Necrosis Factor alpha (TNF?) are also provided.
Type:
Grant
Filed:
February 13, 2024
Date of Patent:
July 29, 2025
Assignee:
ELASMOGEN LTD
Inventors:
Obinna Ubah, Caroline Barelle, Andrew Porter
Abstract: The present invention relates to a synthetic library of humanised antigen specific binding molecules derived from a member of a species in the Elasmobranchii subclass, processes for the production thereof 5 and specific antigen specific binding molecules isolated from said library. The present invention also relates to the multi-domain specific binding molecules comprising humanised Ig-like Novel Antigen Receptor variable domains (VNARs). Specific binding domains that bind to Tumour Necrosis Factor alpha (TNF?) are also provided.
Type:
Application
Filed:
July 26, 2024
Publication date:
November 14, 2024
Applicant:
ELASMOGEN LTD
Inventors:
Caroline Jane BARELLE, Marina KOVALEVA, Laura Ann FERGUSON, Obinna Chukwuemeka UBAH, Andrew Justin Radcliffe PORTER
Abstract: The present invention relates to a synthetic library of humanised antigen specific binding molecules derived from a member of a species in the Elasmobranchii subclass, processes for the production thereof and specific antigen specific binding molecules isolated from said library. The present invention also relates to the multi-domain specific binding molecules comprising humanised Ig-like Novel Antigen Receptor variable domains (VNARs). Specific binding domains that bind to Tumour Necrosis Factor alpha (TNF?) are also provided.
Type:
Grant
Filed:
September 15, 2022
Date of Patent:
September 3, 2024
Assignee:
ELASMOGEN LTD
Inventors:
Caroline Jane Barelle, Marina Kovaleva, Laura Ann Ferguson, Obinna Chukwuemeka Ubah, Andrew Justin Radcliffe Porter
Abstract: The present invention relates to the formation of multi-domain specific binding molecules comprising VNARs. Specific binding domains that bind to Tumour Necrosis Factor alpha (TNF?) are also provided.
Type:
Grant
Filed:
September 27, 2018
Date of Patent:
March 5, 2024
Assignee:
ELASMOGEN LTD
Inventors:
Obinna Ubah, Caroline Barelle, Andrew Porter