Abstract: A method for treatment planning for a radiation therapy system includes setting a number of objectives reflecting clinical criteria are set for the regions of interest and generating radiation dose profiles to be delivered to these regions of interest. A convex optimization function for optimizing the delivered radiation based on the objectives is provided and dose profiles for specific treatment configurations including beam shape settings for the radiation dose profiles are calculated using the convex optimization function. Treatment plans including determining the radiation dose profiles to be delivered during treatment based on the treatment configurations are created and an optimal treatment plan that satisfies the clinical criteria is selected.

Abstract: Methods for dose or treatment planning for a radiotherapy system including a radiotherapy unit are provided. A spatial dose delivered can be changed by adjusting beam shape settings, and the delivered radiation is determined using an optimization problem that steers the delivered radiation according to objectives reflecting criteria for regions of interest including at least one of: targets to be treated during treatment of the patient, organs at risk and/or healthy tissue. The method includes determining an inner set of voxels and providing a first frame description for the inner set of voxels, where the first frame description reflects criteria for the inner set of voxels. Determining an outer set of voxels encompassing the target volume and the inner set of voxels and a frame description for the outer set of voxels is provided where each reflecting criteria for the outer set of voxels. The frame descriptions are then used in the optimization problem that steers the delivered radiation.

Abstract: The present invention relates to the field of radiation therapy and methods, software and systems for treatment planning. A target volume of a region of a patient to be treated during a treatment of a patient in a radiation therapy unit is obtained. A first Isocenter location procedure is performed including inter alia evaluating potential isocenter locations along normal directions of the surface and respective isodistance surfaces in respective starting voxel in a direction inwards from the surface, and a second isocenter location procedure is performed including inter alia identifying a median axis of the target volume or center point of the target volume, placing isocenters at locations along the median axis, placing isocenters in the target volume based on a distance to existing isocenters and to the target surface.

Abstract: In the field of radiotherapy, methods for dose or treatment planning for a radiotherapy system are disclosed, wherein a spatial dose delivered can be adjusted and delivered radiation is determined using an optimization problem that steers the delivered radiation according to a frame description reflecting criteria for regions of interest that include at least one of targets to be treated during treatment of the patient, organs at risk and/or healthy tissue. The method includes estimating a voxel set receiving a higher dose than a predetermined threshold dose level, which voxel set includes voxels from at least one target volume. Further, a low dose voxel set is determined and a frame description for the voxels in the low dose voxel set is provided where voxels receiving a dose exceeding a predetermined threshold value is penalized such that the dose delivered to the low dose voxel set is suppressed. The frame description is then used in the optimization problem that steers the delivered radiation.

Abstract: A method for treatment planning for a radiation therapy system includes setting a number of objectives reflecting clinical criteria are set for the regions of interest and generating radiation dose profiles to be delivered to these regions of interest. A convex optimization function for optimizing the delivered radiation based on the objectives is provided and dose profiles for specific treatment configurations including beam shape settings for the radiation dose profiles are calculated using the convex optimization function. Treatment plans including determining the radiation dose profiles to be delivered during treatment based on the treatment configurations are created and an optimal treatment plan that satisfies the clinical criteria is selected.

Abstract: The present invention relates to the field of radiation therapy. In particular, the present invention relates to methods for treatment planning for a radiation therapy system. The method includes setting a number of objectives reflecting clinical criteria are set for the regions of interest and generating radiation dose profiles to be delivered to these regions of interest. A convex optimization function for optimizing the delivered radiation based on the objectives is provided and dose profiles for specific treatment configurations including beam shape settings for the radiation dose profiles are calculated using the convex optimization function. Treatment plans including determining the radiation dose profiles to be delivered during treatment based on the treatment configurations are created and an optimal treatment plan that satisfies the clinical criteria is selected.

Abstract: A radiotherapy appliance having a plurality of controllable radiation beams which converge on a focus volume wherein an object being irradiated can be movably positioned relative to the focus volume for varying time periods and with varying radiation exposure rates, optimally under control of a computer. The computer controls the focus volume radiation beam size, intensity, and exposure time for subareas of the treatment target in response to a radiation dose distribution determined for the treatment target. A determination of the radiation beam size, intensity, and dwell time of the focus volume in the target area, is made by initially dividing up the specified treatment area into volume elements or voxels and having biological characteristics of the treatment area assigned to each voxel. The energy deposition incident to each voxel to provide this biological characteristic is then calculated.

Abstract: A radiotherapy appliance having a plurality of controllable radiation beams which converge on a focus volume wherein an object being irradiated can be movably positioned relative to the focus volume for varying time periods and with varying radiation exposure rates, optimally under control of a computer. The computer controls the focus volume radiation beam size, intensity, and exposure time for subareas of the treatment target in response to a radiation dose distribution determined for the treatment target. A determination of the radiation beam size, intensity, and dwell time of the focus volume in the target area, is made by initially dividing up the specified treatment area into volume elements or voxels and having biological characteristics of the treatment area assigned to each voxel. The energy deposition incident to each voxel to provide this biological characteristic is then calculated.

Abstract: A stereotactical instrument for identifying a spatial position of an area in a patient's body which is to be subjected to treatment, preferably radiation treatment, the position of the area being previously determined, for example, by an angiogram, PET, DSA, CT, MRI, or X-ray equipment.

Abstract: A radiotherapy appliance having a plurality of controllable radiation beams which converge on a focus volume wherein an object being irradiated can be movably positioned relative to the focus volume for varying time periods and with varying radiation exposure rates, optimally under control of a computer. The computer controls the focus volume radiation beam size, intensity, and exposure time for subareas of the treatment target in response to a radiation dose distribution determined for the treatment target. A determination of the radiation beam size, intensity, and dwell time of the focus volume in the target area, is made by initially dividing up the specified treatment area into volume elements or voxels and having biological characteristics of the treatment area assigned to each voxel. The energy deposition incident to each voxel to provide this biological characteristic is then calculated.

Abstract: A radiotherapy appliance having a plurality of controllable radiation beams which converge on a focus volume wherein an object being irradiated can be movably positioned relative to the focus volume for varying time periods and with varying radiation exposure rates, optimally under control of a computer. The computer controls the focus volume radiation beam size, intensity, and exposure time for subareas of the treatment target in response to a radiation dose distribution determined for the treatment target. A determination of the radiation beam size, intensity, and dwell time of the focus volume in the target area, is made by initially dividing up the specified treatment area into volume elements or voxels and having biological characteristics of the treatment area assigned to each voxel. The energy deposition incident to each voxel to provide this biological characteristic is then calculated.

Abstract: Apparatus for marking a predetermined position of a target for surgical treatment within a patient's brain, comprises a frame for fixedly embracing the patient's skull and having at one side thereof a side-piece provided with a guide extending along a first line, a first support member mounted to the guide for adjustment along the first line and along a second line perpendicular to the first line, a rotatable member supported on the first support member for rotation about a third line perpendicular to the first and second lines, a second support member spaced from the third line and including an arm having a first end attached to the rotatable member and extending longitudinally parallel to the third line in a direction away from a side of the frame opposite the aforementioned one side, the arm thus being adjustable about the third line by rotation of the rotatable member, an arcuate support member mounted to the arm for adjustment along the third line and for adjustment transversely of the arm along an arcua