Patents Assigned to Eleos, Inc.
  • Methods for modulating the efficacy of nucleic acid based therapies
    Patent number: 7960364
    Abstract: Covalently reactive antigen analogs are disclosed herein. The antigens of the invention may be used to stimulate production of catalytic antibodies specific for predetermined antigens associated with particular medical disorders. The antigen analogs may also be used to permanently inactivate endogenously produced catalytic antibodies produced in certain autoimmune diseases as well as in certain lymphoproliferative disorders. Also provided are methods for modulating the efficacy of nucleic acid based therapeutics.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: June 14, 2011
    Assignees: Eleos, Inc.
    Inventors: Dayton T. Reardan, Larry J. Smith, Robert E. Klem