Patents Assigned to ELITechGroup MDX, LLC
  • NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES
    Publication number: 20220119424
    Abstract: Fluorescence quenching nitrodiarylethene analogs are useful in oligonucleotide conjugates and probes. These analogs, whose absorption spectra are substantially blue-shifted relatively to emission spectra of common fluorophores (such as fluorescein), do not need to rely on spectral overlap of quencher absorbance and fluorophore's emission for their quenching abilities. The oligonucleotide-quencher conjugates may be used in detection methods for nucleic acid targets.
    Type: Application
    Filed: December 21, 2021
    Publication date: April 21, 2022
    Applicant: ELITechGroup MDX, LLC
    Inventors: Eugeny A. Lukhtanov, Noah Scarr, Viachaslau Bernat