Patents Assigned to Elixir Medical Corporation
  • Publication number: 20190275013
    Abstract: The present invention provides a pharmaceutical composition comprising a pharmaceutically acceptable excipient and a compound of the formula: wherein R1, R2, R3, R5, R6, R8, M1, M2, M3, M4, M5, M6 and M7 are each independently a member selected from the group consisting of H, C1-6 alkyl, OH and C1-6 hydroxyalkyl; R4, R7 and R9 are each independently selected from the group consisting of C1-6 alkoxy and OH; R10 is a member selected from the group consisting of H, —OH, —OP(O)Me2, —O—(CH2)n—OH and —O—(CH2)m—O—(CH2)o—CH3, wherein subscripts n and m are each independently from 2 to 8 and subscript o is from 1 to 6; each of L1 and L4 are independently selected from the group consisting of: wherein each M8 is independently a member selected from the group consisting of C1-6 alkyl, OH and C1-6 hydroxyalkyl; each of L2 and L3 are independently selected from the group consisting of: and salts, hydrates, isomers, metabolites, N-oxides and prodrugs thereof.
    Type: Application
    Filed: October 8, 2018
    Publication date: September 12, 2019
    Applicant: Elixir Medical Corporation
    Inventors: John Yan, Xiaoxia Zheng, Vinayak D. Bhat
  • Patent number: 10383750
    Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: August 20, 2019
    Assignee: Elixir Medical Corporation
    Inventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn Serna
  • Publication number: 20190231564
    Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.
    Type: Application
    Filed: March 18, 2019
    Publication date: August 1, 2019
    Applicant: Elixir Medical Corporation
    Inventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn Serna
  • Patent number: 10350093
    Abstract: Devices and methods are provided for an implantable medical device which is degradable over a clinically relevant period of time. The medical devices may have the form of implants, graft implants, vascular implants, non vascular implants, wound closure implants, sutures, drug delivery implants, biologic delivery implants, urinary tract implants, inter-uterine implants, organ implants, bone implants including bone plates, bone screws, dental implants, spinal disks, or the like. In preferred embodiments, the implantable medical device comprises an implantable luminal prosthesis, such as vascular and non-vascular stents and stents grafts.
    Type: Grant
    Filed: December 23, 2015
    Date of Patent: July 16, 2019
    Assignee: Elixir Medical Corporation
    Inventors: John Yan, Motasim Sirhan, Brett Cryer, Vinayak Bhat
  • Publication number: 20190201225
    Abstract: A stent or other luminal prosthesis is delivered by a catheter having a contoured balloon. The contoured balloon may include a central dome region flanked by at least one adjacent flat or cylindrical region. The central domed region and adjacent flat or cylindrical regions are joined at shallow angles to provide for an incrementally larger expansion of the center region of the stent while minimizing shear forces during expansion.
    Type: Application
    Filed: March 5, 2019
    Publication date: July 4, 2019
    Applicant: Elixir Medical Corporation
    Inventors: Motasim Sirhan, Udayan G. Patel
  • Patent number: 10271976
    Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: April 30, 2019
    Assignee: Elixir Medical Corporation
    Inventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn Serna
  • Publication number: 20190070334
    Abstract: Luminal prostheses comprise scaffolds having coatings adhered to at least a portion of their outer surfaces. The surfaces are modified to enhance binding of the coatings. For example, the surfaces may be microblasted, laser treated, chemically etched, exposed to plasma, or exposed to a corona discharge, allowing a polymeric coating to adhere to the scaffold more tightly than in the absence of the surface modification. The coatings can be used to deliver therapeutic or other agents dispersed therein.
    Type: Application
    Filed: March 2, 2018
    Publication date: March 7, 2019
    Applicant: Elixir Medical Corporation
    Inventors: John Yan, Howard Huang, Vinayak D. Bhat
  • Publication number: 20180360628
    Abstract: A biodegradable stent prosthesis formed from a degradable material, having a plurality of luminal, abluminal, and side surface regions, wherein a surface portion extending between the abluminal and luminal surface region of at least some structural elements is convex.
    Type: Application
    Filed: December 8, 2017
    Publication date: December 20, 2018
    Applicant: Elixir Medical Corporation
    Inventors: John Yan, Vinayak Bhat
  • Patent number: 10123996
    Abstract: A pharmaceutical composition comprising a pharmaceutically acceptable excipient and a compound of the formula: wherein R1, R2, R3, R5, R6, R8, M1, M2, M3, M4, M5, M6 and M7 are each independently a member selected from the group consisting of H, C1-6 alkyl, OH and C1-6 hydroxyalkyl; R4, R7 and R9 are each independently selected from the group consisting of C1-6 alkoxy and OH; R10 is a member selected from the group consisting of H, —OH, —OP(O)Me2, —O—(CH2)n—OH and —O—(CH2)m—O—(CH2)o—CH3, wherein subscripts n and m are each independently from 2 to 8 and subscript o is from 1 to 6; each of L1 and L4 are independently selected from the group consisting of: wherein each M8 is independently a member selected from the group consisting of C1-6 alkyl, OH and C1-6 hydroxyalkyl; each of L2 and L3 are independently selected from the group consisting of: and salts, isomers, or N-oxides thereof.
    Type: Grant
    Filed: June 13, 2016
    Date of Patent: November 13, 2018
    Assignee: Elixir Medical Corporation
    Inventors: John Yan, Xiaoxia Zheng, Vinayak D. Bhat
  • Publication number: 20180318113
    Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.
    Type: Application
    Filed: July 18, 2018
    Publication date: November 8, 2018
    Applicant: Elixir Medical Corporation
    Inventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn Serna
  • Patent number: 10076431
    Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: September 18, 2018
    Assignee: Elixir Medical Corporation
    Inventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn Serna
  • Publication number: 20180200091
    Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.
    Type: Application
    Filed: March 14, 2018
    Publication date: July 19, 2018
    Applicant: Elixir Medical Corporation
    Inventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn S. Serna
  • Patent number: 9943426
    Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: April 17, 2018
    Assignee: Elixir Medical Corporation
    Inventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn S. Serna
  • Patent number: 9937280
    Abstract: Luminal prostheses comprise scaffolds having coatings adhered to at least a portion of their outer surfaces. The surfaces are modified to enhance binding of the coatings. For example, the surfaces may be microblasted, laser treated, chemically etched, exposed to plasma, or exposed to a corona discharge, allowing a polymeric coating to adhere to the scaffold more tightly than in the absence of the surface modification. The coatings can be used to deliver therapeutic or other agents dispersed therein.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: April 10, 2018
    Assignee: Elixir Medical Corporation
    Inventors: John Yan, Howard Huang, Vinayak D. Bhat
  • Patent number: 9855156
    Abstract: A biodegradable stent prosthesis formed from a degradable material, having a plurality of luminal, abluminal, and side surface regions, wherein a surface portion extending between the abluminal and luminal surface region of at least some structural elements is convex.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: January 2, 2018
    Assignee: Elixir Medical Corporation
    Inventors: John Yan, Vinayak Bhat
  • Publication number: 20170290686
    Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.
    Type: Application
    Filed: May 25, 2017
    Publication date: October 12, 2017
    Applicant: Elixir Medical Corporation
    Inventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn S. Serna
  • Patent number: 9730819
    Abstract: A biodegradable stent prosthesis formed from a degradable material, having a plurality of luminal, abluminal, and side surface regions, wherein a surface portion extending between the abluminal and luminal surface region of at least some structural elements is convex.
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: August 15, 2017
    Assignee: Elixir Medical Corporation
    Inventors: John Yan, Vinayak Bhat
  • Publication number: 20170156899
    Abstract: The disclosure provides biodegradable implantable devices such as a stent comprising a biodegradable polymeric wherein the polymeric material is treated to control crystallinity and/or Tg. The stent is capable to expand at body temperature in a body lumen from a crimped configuration to a deployed diameter and have sufficient strength to support a body lumen.
    Type: Application
    Filed: January 31, 2017
    Publication date: June 8, 2017
    Applicant: Elixir Medical Corporation
    Inventors: Xiaoxia Zheng, John Yan, Vinayak Bhat
  • Patent number: 9566371
    Abstract: The disclosure provides biodegradable implantable devices such as a stent comprising a biodegradable polymeric wherein the polymeric material is treated to control crystallinity and/or Tg. The stent is capable to expand at body temperature in a body lumen from a crimped configuration to a deployed diameter and have sufficient strength to support a body lumen.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: February 14, 2017
    Assignee: Elixir Medical Corporation
    Inventors: Xiaoxia Zheng, John Yan, Vinayak Bhat
  • Patent number: 9480588
    Abstract: A biodegradable stent prosthesis formed from a degradable material, having a plurality of luminal, abluminal, and side surface regions, wherein a surface portion extending between the abluminal and luminal surface region of at least some structural elements is convex or bulbous and optionally, where at least some of the abluminal surface regions may be concave.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: November 1, 2016
    Assignee: Elixir Medical Corporation
    Inventors: John Yan, Vinayak Bhat