Abstract: A method for treating AR+ breast cancer in a subject comprising administering to the subject an AR agonist (e.g., SARMs such as RAD140), or in combination with one or more therapeutic agents selected from the group consisting of cdk4/6 inhibitors, m-TOR inhibitors, PI3k inhibitors, PARP inhibitors, BCL-2 inhibitors, and MCL-1 inhibitors.
Type:
Grant
Filed:
November 26, 2019
Date of Patent:
October 3, 2023
Assignee:
Ellipses Pharma Ltd.
Inventors:
Gary Hattersley, Jamal Saeh, Ziyang Yu, Chris Miller, Teeru Bihani