Abstract: A phototherapy device comprising a plurality of light sources adapted for emitting at a treatment wavelength and a contact layer, wherein the contact layer is adapted to retain a treatment fluid, the plurality of light sources are electrically isolated from treatment fluid retained by the contact layer, and the plurality of light sources are coupled to the contact layer. The plurality of light sources can be releasably coupled or permanently coupled to the contact layer. A phototherapy kit comprising the phototherapy device and instructions for selection or placement of the plurality of lights, or for selection of settings for the plurality of lights, on phototherapy device. The phototherapy device or kit can also include a liquid treatment absorbed in the contact layer or to be applied to the contact layer. A method of treating tissue, comprising applying electromagnetic radiation to tissue using the phototherapy device.