Abstract: Disclosed is an apparatus for processing body fluids which in one embodiment includes a support having ethylenediamine tetraacetic acid, and N-tosyl-lysyl chloromethylketone and/or N-tosyl-phenylalanyl chloromethylketone.

Abstract: Disclosed is a composition useful in the processing of blood and cerebrospinal fluid to help maintain sample integrity for analytical testing. The composition generally includes a first enzyme inhibitor selected from the group of enzyme inhibitors consisting of inhibitors which allow substantially the function of metalo-peptidase while inhibiting at least one enzyme selected from the group of enzymes consisting of endopeptidase, exopeptidase and sulfhydryl-mediated proteases, and inhibitors which substantially inhibit the function of metalo-peptidase, wherein where the first enzyme inhibitor inhibits metalo-peptidase, the assaying composition further comprises a second enzyme inhibitor suitable to inhibit at least one enzyme selected from the group of enzymes consisting of endopeptidase, exopeptidase, metalo-peptidase and sulfhydryl-mediated proteases. Further disclosed is an apparatus which includes a tube containing the inhibitors into which the bodyfluids are placed.