Abstract: The present invention is directed to a modified poxvirus vector that allows for the generation of recombinant poxviruses by a single recombination event. A modified poxvirus vector comprising at least one reporter gene located between two flanking sequences for homologous recombination is disclosed. Furthermore, a host cell comprising said vector and a method for the generation of recombinant poxviruses using said vector are provided.
Type:
Application
Filed:
December 16, 2009
Publication date:
February 2, 2012
Applicant:
EMERGENT PRODUCT DEVELOPMENT GERMANY GMBH