Patents Assigned to Emergent Product Development United Kingdom
  • USE OF E. COLI SURFACE ANTIGEN 3 SEQUENCES FOR THE EXPORT OF HETEROLOGOUS ANTIGENS
    Publication number: 20120064114
    Abstract: The present invention provides an export signal system based on E. coli CS3 antigen for directing the secretion of foreign antigens from host cells. In particular, the invention describes genetic constructs encoding fusion proteins that contain a CS3 export signal fused to at least one heterologous amino acid sequence. Attenuated microorganisms expressing the fusion proteins and pharmaceutical compositions comprising such attenuated microorganisms are also disclosed.
    Type: Application
    Filed: October 21, 2009
    Publication date: March 15, 2012
    Applicant: Emergent Product Development United Kingdom
    Inventors: Jonathan Telfer, Mark Richard Redfern