Patents Assigned to Emery University
  • Production of streptococcal M protein
    Patent number: 5840314
    Abstract: Methods and compositions are provided for the cloning and expression of Streptococcus pyogenes M protein genes, and, in particular, types 5, 6 and 24 gene in single-cell host organisms. The streptococcal M protein produced by the recombinant DNA techniques described herein may be formulated for use as immunogens in vaccines to protect against S. pyogenes infections. The gene for the M protein may further be employed as a molecular probe for the accurate identification of streptococci in infected body tissues and fluids.
    Type: Grant
    Filed: February 22, 1994
    Date of Patent: November 24, 1998
    Assignees: The Rockefeller University, Emery University
    Inventors: June Rothman Scott, Vincent Angelo Fischetti