Abstract: A molecule for use in a method of treatment or diagnosis of Kawasaki Disease in an individual, the molecule comprising: (a) CACNA2D3; (b) CAMK2D; (c) KCNIP4; (d) ANGPT1; (e) NAALADL2; (f) ZFHX3; (g) MPHOSPH10; (h) a sequence having at least 90% sequence identity to any of (a) to (g); or (i) a modulator of any of (a) to (e). We also describe the use of Pregabalin ((3S)-3-(aminomethyl)-5-methyl-hexanoic acid) in the treatment or prevention of Kawasaki Disease in an individual.
Type:
Application
Filed:
May 11, 2009
Publication date:
December 10, 2009
Applicants:
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR), EMMA CHILDREN'S HOSPITAL, UNIVERSITY OF WESTERN AUSTRALIA
Inventors:
Taco Kuijpers, Martin Lloyd Hibberd, David Paul Burgner, Sonia Maria Davila Dominguez