Patents Assigned to Emory University, Inc.
  • Therapeutic nucleosides
    Patent number: 7053100
    Abstract: The use of a 1,3-oxathiolane nucleoside analogue and pharmaceutically acceptable derivatives thereof for the treatment of hepatitis B virus infections is disclosed. Pharmaceutical formulations are also provided.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: May 30, 2006
    Assignee: Emory University, Inc.
    Inventor: Dennis C. Liotta
  • Therapeutic nucleosides
    Publication number: 20040242610
    Abstract: The use of a 1,3-oxathiolane nucleoside analogue and pharmaceutically acceptable derivatives thereof for the treatment of hepatitis B virus infections is disclosed. Pharmaceutical formulations are also provided.
    Type: Application
    Filed: July 9, 2004
    Publication date: December 2, 2004
    Applicant: Emory University, Inc.
    Inventor: Dennis C. Liotta
  • Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers
    Publication number: 20040171124
    Abstract: A process for the resolution of a racemic mixture of nucleoside enantiomers that includes the step of exposing the racemic mixture to an enzyme that preferentially catalyzes a reaction in one of the enantiomers. The nucleoside enantiomer (−)-2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner.
    Type: Application
    Filed: March 5, 2004
    Publication date: September 2, 2004
    Applicant: Emory University, Inc.
    Inventors: Dennis C. Liotta, Raymond F. Schinazi, Woo-Baeg Choi