Abstract: Levothyroxine, also known as L-thyroxine, synthetic T4, or 3,5,3?,5?-tetraiodo-L-thyronine, CAS number 51-48-9, is a synthetic form of thyroxine, used as a hormone substitute for patients with thyroid conditions. The invention relates to a method for the preparation of an oral levothyroxine composition. The method according to the invention results in liquid levothyroxine formulations that have improved storage stability compared to known liquid levothyroxine formulations.
Type:
Grant
Filed:
March 10, 2011
Date of Patent:
June 9, 2015
Assignee:
EMP Pharma GmbH
Inventors:
Yannis Psarrakis, Konstantinos I. Lioumis
Abstract: Levothyroxine, also known as L-thyroxine, synthetic T4, or 3,5,3?,5?-tetraiodo-L-thyronine, CAS number 51-48-9, is a synthetic form of thyroxine, used as a hormone substitute for patients with thyroid conditions. The invention relates to a method for the preparation of an oral levothyroxine composition. The method according to the invention results in liquid levothyroxine formulations that have improved storage stability compared to known liquid levothyroxine formulations.
Type:
Application
Filed:
March 10, 2011
Publication date:
March 13, 2014
Applicant:
EMP Pharma GmbH
Inventors:
Yannis Psarrakis, Konstantinos I. Lioumis