Abstract: Provided herein is a process for the preparation of 3,4-methylenedioxymethamphetamine, (R)-3,4-methylenedioxymethamphetamine and (S)-3,4-methylenedioxymethamphetamine.
Abstract: Provided herein are compounds of Formula (I), Formula (II), and Formula (III) or pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7 and A are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I), Formula (II), or Formula (III) and methods of using a compound of Formula (I), Formula (II), or Formula (III), e.g., in the treatment of a mental health disease or disorder.
Type:
Grant
Filed:
December 28, 2022
Date of Patent:
February 27, 2024
Assignee:
EmpathBio, Inc.
Inventors:
Robert B. Perni, Glenn Short, Tanweer A. Khan
Abstract: The present disclosure provides prodrug compounds of MDMA, MDA, and derivatives thereof having an improved pharmacokinetic profile suitable for the treatment of various neurological diseases.
Type:
Grant
Filed:
October 3, 2022
Date of Patent:
December 19, 2023
Assignee:
EmpathBio, Inc.
Inventors:
Srinivas Rao, Glenn Short, Robert B. Perni, Tanweer A. Khan, Alan C. Gibbs